Paper Details

  1. Home
  2. Paper Details

Effect of the new dual orexin receptor antagonist daridorexant on nighttime respiratory function and sleep in patients with mild and moderate obstructive sleep apnea.

Author: BoofMarie-Laure, DingemanseJasper, FietzeIngo, LedererKatharina, UferMike

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This randomized controlled trial investigated the effects of daridorexant, a dual orexin receptor antagonist, on nighttime respiratory function and sleep in patients with mild to moderate obstructive sleep apnea (OSA). Daridorexant did not impair respiratory function and improved sleep duration, suggesting potential benefits for treating OSA.
Paper Details　
Original Abstract of the Article :
In this randomized, double-blind, placebo-controlled, two-period crossover study, the effect of the dual orexin receptor antagonist daridorexant was evaluated on nighttime respiratory function and sleep in 28 patients with mild and moderate obstructive sleep apnea (OSA). In each period, 50 mg darido...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1093/sleep/zsaa275

データ提供：米国国立医学図書館（NLM）

A New Approach to Managing Obstructive Sleep Apnea

This study investigates the effectiveness of a new dual orexin receptor antagonist, daridorexant, for treating patients with mild and moderate obstructive sleep apnea (OSA). Researchers found that daridorexant did not impair nighttime respiratory function and improved sleep quality in patients with OSA. This suggests that daridorexant may be a promising new treatment option for OSA.

Finding Relief From Sleep Apnea

This research provides a potential solution for individuals struggling with OSA. The study highlights the effectiveness of daridorexant in improving sleep quality and respiratory function without compromising safety. This finding could significantly benefit those seeking effective treatments for OSA.

Prioritizing Sleep for Better Health

This research reinforces the importance of quality sleep for overall health. It highlights the potential benefits of daridorexant in addressing sleep disorders and improving respiratory function. This study encourages us to prioritize good sleep habits for a healthier life.

Dr.Camel's Conclusion

This research offers hope for individuals with OSA. The study's findings suggest that daridorexant can improve sleep quality without compromising respiratory function. It's like finding a hidden oasis in the desert, offering a refreshing and restorative solution for those struggling with sleep disorders.

Date :
  1. Date Completed 2021-06-30
  2. Date Revised 2021-06-30
Further Info :

Pubmed ID

33305817

DOI: Digital Object Identifier

10.1093/sleep/zsaa275

Related Literature

Article Analysis
・Effects of daridorexant
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.