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Targeted Therapies for Skeletal Muscle Ion Channelopathies: Systematic Review and Steps Towards Precision Medicine.

Author: AltamuraConcetta, DesaphyJean-François, FontaineBertrand, VicartSavine

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This article provides an overview of skeletal muscle ion channelopathies, including non-dystrophic myotonias, periodic paralyses, congenital myasthenic syndrome, and congenital myopathies. The treatment for these disorders is primarily symptomatic.
Paper Details　
Original Abstract of the Article :
Skeletal muscle ion channelopathies include non-dystrophic myotonias (NDM), periodic paralyses (PP), congenital myasthenic syndrome, and recently identified congenital myopathies. The treatment of these diseases is mainly symptomatic, aimed at reducing muscle excitability in NDM or modifying trigger...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203248/

データ提供：米国国立医学図書館（NLM）

Targeted Therapies for Skeletal Muscle Ion Channelopathies: A Journey Toward Precision Medicine

In the vast desert of medical science, the study of skeletal muscle ion channelopathies is a captivating journey. This research, akin to a caravan equipped with advanced tools for navigating the intricate workings of the body, explores the potential of targeted therapies for these disorders, which affect muscle excitability. The study highlights the need for precision medicine, a tailored approach to treatment that takes into account individual genetic and physiological characteristics. It's like using a compass to pinpoint the exact location of a hidden spring, ensuring that the right treatment reaches the right muscle.

A New Era of Precision Medicine for Muscle Disorders

The study emphasizes the importance of understanding the specific mechanisms underlying each type of ion channelopathy, a complex desert landscape of genetic mutations and physiological dysfunctions. This knowledge will pave the way for personalized treatments that address the unique needs of each patient, offering a glimmer of hope for those struggling with muscle weakness and fatigue.

The Promise of Tailored Therapies

By pinpointing the root causes of these disorders, researchers can develop targeted therapies that address the specific dysfunction, rather than relying on generic approaches. This approach, akin to a skilled desert guide leading a caravan through treacherous terrain, holds the promise of more effective and targeted treatments for skeletal muscle ion channelopathies.

Dr. Camel's Conclusion

This research underscores the crucial role of precision medicine in tailoring treatments to individual needs. It's a reminder that the human body is a vast and complex desert, requiring a personalized approach to navigate its unique challenges.
Date :
  1. Date Completed 2021-11-15
  2. Date Revised 2021-11-15
Further Info :

Pubmed ID

33325393

DOI: Digital Object Identifier

PMC8203248

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Languages

English

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