Risk of foetal harm with letrozole use in fertility treatment: a systematic review and meta-analysis.

Author: AchilliChiara, BhidePriya, CoomarasamyArri, LegroRichard S, PundirJyotsna, RombautsLuk, SabatiniLuca, TeedeHelena, ThangaratinamShakila, ZamoraJavier

Paper Details 
Original Abstract of the Article :
The aromatase inhibitor letrozole is increasingly recommended for ovulation induction, as it is more effective with fewer side-effects than other agents. But many clinicians are reluctant to use the drug for fertility treatment due to a strong-label warning against its use, which warns about congeni...See full text at original site
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引用元:
https://doi.org/10.1093/humupd/dmaa055

データ提供:米国国立医学図書館(NLM)

Letrozole for Fertility Treatment: Balancing Benefits and Risks

This systematic review and meta-analysis investigates the use of letrozole, an aromatase inhibitor, for ovulation induction in women seeking pregnancy. Imagine a desert gardener cultivating a fertile oasis, using carefully selected tools and techniques to promote growth and nurture life. This study explores the potential of letrozole to help women achieve pregnancy, weighing its effectiveness against potential risks. The authors reviewed existing research on letrozole use in fertility treatment, finding that it is generally well-tolerated and more effective than other agents. However, they acknowledge the concerns surrounding the potential for foetal harm and highlight the need for careful consideration and informed decision-making.

A Fertile Oasis: Cultivating a Healthy Pregnancy

This study provides valuable insights into the potential benefits and risks of letrozole for fertility treatment. Imagine a desert gardener carefully tending to a precious seed, nurturing its growth and protecting it from harm. Similarly, healthcare providers need to carefully consider the potential risks and benefits of letrozole when treating women seeking pregnancy. This research underscores the importance of open communication, informed consent, and careful monitoring to maximize the potential for a successful and healthy pregnancy.

Navigating the Desert of Fertility: A Collaborative Journey

This review emphasizes the importance of collaboration between healthcare providers and patients in fertility treatment. Imagine a desert traveler embarking on a journey, relying on a trusted guide to navigate the challenging terrain. Similarly, women seeking pregnancy need to partner with their healthcare providers to make informed decisions about fertility treatments. This research highlights the need for open communication, shared decision-making, and careful monitoring to ensure the best possible outcomes for both mothers and their babies.

Dr. Camel's Conclusion

This review provides valuable insights into the potential benefits and risks of letrozole for fertility treatment, urging healthcare providers to weigh these factors carefully in their practice. Just as a desert traveler needs to be aware of the terrain and potential obstacles, fertility specialists need to be mindful of the potential risks and benefits of different treatment options. By working collaboratively with patients and making informed decisions, healthcare providers can help women achieve their dream of a healthy pregnancy.
Date :
  1. Date Completed 2022-03-01
  2. Date Revised 2022-03-01
Further Info :

Pubmed ID

33374012

DOI: Digital Object Identifier

10.1093/humupd/dmaa055

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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