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Survival outcomes in sinonasal carcinoma with neuroendocrine differentiation: A NCDB analysis.

Author: Abi HachemRalph, AckallFeras, IssaKhalil, JangDavid W, JungSin-Ho, LiJianghao, RangarajanSanjeet V

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study analyzed treatment outcomes in patients with sinonasal carcinoma with neuroendocrine differentiation (SCND) using the National Cancer Database. The study found that SCND appears to be best treated using a multimodality approach with definitive chemoradiation (CRT) or surgery followed by CRT. The study suggests that neoadjuvant chemotherapy could be helpful in selecting the best treatment strategy for SCND.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Sinonasal carcinoma with neuroendocrine differentiation (SCND) is a rare group of tumors with poor prognosis. Treatment and sequence of therapies are still unclear. The goal of this study is to analyze treatment outcomes in SCND using a national database. METHODS: The National Cancer Da...See full text at original site
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引用元：
https://doi.org/10.1016/j.amjoto.2020.102851

データ提供：米国国立医学図書館（NLM）

Treatment Outcomes in Sinonasal Carcinoma with Neuroendocrine Differentiation

The journey to treat sinonasal carcinoma with neuroendocrine differentiation (SCND) is a challenging one, navigating the complexities of this rare and aggressive cancer. This study analyzed treatment outcomes in SCND patients using the National Cancer Database, highlighting the importance of a multimodality approach to manage this disease. The researchers found that patients treated with definitive chemoradiation (CRT) or surgery followed by CRT had significantly better overall survival. This study underscores the crucial role of multimodality therapies in improving outcomes for SCND patients.

Multimodality Therapies: A Key to Improved Survival in SCND

The study found that multimodality therapies, specifically definitive CRT or surgery followed by CRT, were associated with significantly better overall survival for SCND patients. This finding highlights the importance of integrating different treatment modalities, such as surgery, radiation therapy, and chemotherapy, to effectively manage this aggressive cancer.

Navigating the Desert of SCND Treatment

SCND is a rare and challenging cancer with a poor prognosis. This study provides valuable insights into treatment strategies, emphasizing the potential benefits of a multimodality approach. It underscores the importance of careful patient selection and the use of neoadjuvant chemotherapy to optimize treatment strategies and improve outcomes for SCND patients. This research guides us as we continue to navigate the vast desert of cancer treatment, seeking innovative approaches to improve patient outcomes.

Dr. Camel's Conclusion

This study underscores the importance of a multimodality approach in treating sinonasal carcinoma with neuroendocrine differentiation (SCND). Definitive CRT or surgery followed by CRT demonstrated significantly better overall survival. This research provides valuable guidance for clinicians and offers hope for improved outcomes for SCND patients. As a wise camel, I recognize the importance of ongoing research in refining treatment strategies and improving the lives of patients battling this challenging cancer.

Date :
  1. Date Completed 2021-09-09
  2. Date Revised 2021-09-09
Further Info :

Pubmed ID

33385873

DOI: Digital Object Identifier

10.1016/j.amjoto.2020.102851

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Languages

English

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