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Bromelain reduced pro-inflammatory mediators as a common pathway that mediate antinociceptive and anti-anxiety effects in sciatic nerve ligated Wistar rats.
Author: BakareAhmed O, OwoyeleBamidele V
Original Abstract of the Article :
The involvement of pro-inflammatory mediators complicates the complex mechanism in neuropathic pain (NP). This study investigated the roles of bromelain against pro-inflammatory mediators as a mechanism that underpins its antinociceptive and anti-anxiety effects in the peripheral model of NP. Sixty-...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801445/
データ提供:米国国立医学図書館(NLM)
Bromelain: A Desert Oasis for Neuropathic Pain
Neuropathic pain, a debilitating condition that arises from damage to the nervous system, can feel like a constant, unrelenting desert heat. This research investigates the potential of bromelain, a protein found in pineapple, as a therapeutic agent for neuropathic pain. The researchers used a rat model of neuropathic pain and evaluated bromelain's effectiveness in reducing pain and anxiety symptoms. The findings offer promising insights into the potential of bromelain as a natural remedy for neuropathic pain.
Cooling Down the Desert Heat
The study demonstrated that bromelain significantly reduced pain and anxiety in rats with neuropathic pain. The researchers also found that bromelain effectively reduced levels of inflammatory mediators in the brain and sciatic nerve. These findings suggest that bromelain may offer a natural and effective way to cool down the desert heat of neuropathic pain.
Finding Relief in the Desert
The research highlights the potential benefits of bromelain for individuals suffering from neuropathic pain. However, further research is needed to determine the optimal dose and safety of bromelain in humans. It's a promising oasis in the desert of neuropathic pain, but continued exploration is essential to ensure its effectiveness and safety for human use.
Dr.Camel's Conclusion
Neuropathic pain can feel like a never-ending desert heat. This research explores bromelain, a pineapple protein, as a potential oasis of relief. The findings show promise, suggesting that bromelain can effectively reduce pain and anxiety in a rat model. Further research is needed to confirm these findings in humans. This exciting discovery offers hope for those seeking natural solutions for neuropathic pain.
Date :
- Date Completed 2021-08-05
- Date Revised 2021-08-05
Further Info :
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