Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop.

Author: AmanM Javad, BanadygaLogan, CaoWenguang, ChengKeding, Embury-HyattCarissa, FranaszekKrzysztof, HeShihua, HowellKatie A, KailasanShweta, LeungAnders, MoffatEstella, QiuXiangguo, SiragamVinayakumar, YanFeihu, ZhuWenjun

Paper Details 
Original Abstract of the Article :
Ebola virus (EBOV) is responsible for numerous devastating outbreaks throughout Africa, including the 2013-2016 West African outbreak as well as the two recent outbreaks in the Democratic Republic of the Congo (DRC), one of which is ongoing. Although EBOV disease (EVD) has typically been considered ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7844533/

データ提供:米国国立医学図書館(NLM)

Ebola Virus: Unmasking the Hidden Dangers in the Desert of Infection

Ebola virus, like a deadly mirage in the desert, has long been a formidable threat to human health. This research, like a vigilant desert sentinel, investigates a case of atypical Ebola virus disease in a nonhuman primate, shedding light on the potential for viral persistence and recrudescent disease. The authors, like skilled trackers, meticulously analyze the viral mutations and their impact on disease progression, revealing a new and alarming aspect of Ebola virus infection.

Ebola Virus: A New Threat Emerging from the Sands of Infection

This research, like a sandstorm sweeping across the desert, reveals a new and concerning aspect of Ebola virus infection. The study demonstrates that viral mutations can lead to atypical disease presentations, including viral persistence and recrudescent disease. This is like discovering a hidden spring of poison water in the desert, revealing a danger that was previously unknown. The findings highlight the importance of continued research into Ebola virus and its potential to evade treatment and cause recurring infections.

The Importance of Continued Research in Understanding Ebola Virus

This research, like a warning sign in the desert, underscores the importance of continued research into Ebola virus. It is crucial to understand the complex dynamics of this virus and its potential for evolving and causing unexpected complications. This knowledge can help us develop more effective treatments and prevention strategies to protect against this deadly threat.

Dr. Camel's Conclusion

This research provides a sobering reminder of the unpredictable nature of Ebola virus. The study highlights the potential for viral mutations to lead to atypical disease presentations, including viral persistence and recrudescent disease. I believe that this research will motivate further investigation into the complexities of Ebola virus infection and help us develop more effective strategies for preventing and treating this deadly disease.

Date :
  1. Date Completed 2021-09-07
  2. Date Revised 2021-09-07
Further Info :

Pubmed ID

33436428

DOI: Digital Object Identifier

PMC7844533

Related Literature

SNS
PICO Info
in preparation
Languages

English

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