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Surrogate testing of oral third-generation cephalosporin susceptibility to common uropathogens.
Author: BurchCynthia, LeberAmy L, WatsonJoshua R
Original Abstract of the Article :
Cefazolin susceptibility of urine isolates of Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis predicts susceptibility to oral cephalosporins, but cefazolin-resistant isolates may be susceptible to oral third-generation cephalosporins. Among 194 urine isolates, we found >95% categorica...See full text at original site
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引用元:
https://doi.org/10.1016/j.diagmicrobio.2020.115299
データ提供:米国国立医学図書館(NLM)
Cephalosporin Susceptibility: A Surrogate Testing Approach
This study explores the use of surrogate testing to predict the susceptibility of common uropathogens to oral third-generation cephalosporins. Think of surrogate testing as a camel caravan using a scout to assess the terrain ahead before embarking on a perilous journey. The researchers investigated whether cefazolin susceptibility could be used as a proxy for predicting susceptibility to other oral cephalosporins, such as cefpodoxime, cefdinir, and cefixime.
Cefazolin: A Valuable Proxy
The study found that cefazolin susceptibility was a reliable predictor for susceptibility to other oral cephalosporins, with high categorical agreement. This is like a camel caravan relying on a reliable scout to provide accurate information about the terrain, ensuring a safer and smoother journey. The study suggests that cefazolin can be used as a surrogate test to guide antibiotic selection for urinary tract infections.
Smart Antibiotic Choices: Optimizing Treatment
This research highlights the potential benefits of surrogate testing in guiding antibiotic choices for urinary tract infections. By utilizing cefazolin as a surrogate test, healthcare professionals can potentially optimize treatment outcomes and minimize unnecessary antibiotic use. This is like a camel caravan using a smart map to navigate a vast desert, ensuring that they take the most efficient and safe route to their destination.
Dr.Camel's Conclusion
This study underscores the potential of surrogate testing to streamline antibiotic selection for urinary tract infections. By using cefazolin as a proxy for predicting susceptibility to other oral cephalosporins, healthcare professionals can potentially optimize treatment outcomes and minimize unnecessary antibiotic use. This is like a camel caravan relying on a wise guide to choose the most appropriate path through the desert.
Date :
- Date Completed 2021-08-16
- Date Revised 2021-08-16
Further Info :
Related Literature
English
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