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Raloxifene-induced osteonecrosis of the jaw (MRONJ) with no exposure to bisphosphonates: clinical and radiographic findings.
Author: BindakhilMohammed, MupparapuMel, ShantiRabie M
Original Abstract of the Article :
Raloxifene is a selective estrogen receptor modulator (SERM) that is used to manage osteoporosis in women. Because of its tissue selectivity, raloxifene has fewer side effects than estrogen therapy; however, raloxifene-associated osteonecrosis of the jaw (ONJ) has recently been reported. While most...See full text at original site
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引用元:
https://doi.org/10.3290/j.qi.b912675
データ提供:米国国立医学図書館(NLM)
Raloxifene-Induced Osteonecrosis of the Jaw: A Complication to Watch For
Osteonecrosis of the jaw (ONJ), like a sudden desert storm, can inflict significant damage. This research investigates a rare complication, [raloxifene] -induced ONJ, in a patient with [cemento-osseous dysplasia] . It's like discovering a hidden sandstorm in a seemingly serene desert landscape, reminding us that even seemingly safe situations can harbor unexpected dangers.
Raloxifene's Potential for Osteonecrosis
The case report highlights the potential of [raloxifene] , a medication used to manage osteoporosis, to induce [ONJ] , even without prior exposure to [bisphosphonates] . This discovery underscores the importance of careful monitoring for [ONJ] in patients taking [raloxifene] , even those with preexisting conditions like [cemento-osseous dysplasia] . It's like finding a hidden patch of quicksand in the desert, prompting us to take extra caution when navigating the terrain of medication use.
Caution and Vigilance in Dental Practice
This study emphasizes the need for dental practitioners to be vigilant about [raloxifene] -associated [ONJ] , especially in patients with [cemento-osseous dysplasia] . It underscores the importance of proactive measures to prevent and manage this complication, like building a sturdy oasis in the desert to protect against the threat of sandstorms.
Dr.Camel's Conclusion
This research highlights a rare but potentially serious complication associated with [raloxifene] use. It's a reminder that even seemingly benign medications can have unexpected side effects, like a hidden sandstorm in a desert landscape. This study underscores the importance of awareness, vigilance, and proactive management in dental practice, ensuring the safety and well-being of patients.
Date :
- Date Completed 2021-01-26
- Date Revised 2023-10-31
Further Info :
Related Literature
English
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