Deferasirox-associated Fanconi syndrome in adult patients with transfusional iron overload.

Author: GearaAbdallah, SayaniFarzana, YuiJennifer C

Paper Details 
Original Abstract of the Article :
Deferasirox is an oral chelator approved for iron overload, which has a potential side effect of renal Fanconi syndrome, with proximal tubular dysfunction and tubular acidosis. Monitoring of renal function is recommended, though no standard for monitoring exists. We aim to describe cases of deferasi...See full text at original site
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引用元:
https://doi.org/10.1111/vox.13064

データ提供:米国国立医学図書館(NLM)

Deferasirox and Fanconi Syndrome: A Delicate Balancing Act

Iron overload is a serious condition that can damage organs, and deferasirox is a medication used to treat it. This research explores a potential side effect of deferasirox: Fanconi syndrome, a disorder that affects the kidneys' ability to filter waste. The study sheds light on the importance of careful monitoring of kidney function in patients taking this medication.

The researchers describe cases of Fanconi syndrome in adults who were taking deferasirox. This syndrome, like a clogged filter in a desert oasis, prevents the kidneys from effectively removing waste products from the body. While deferasirox has the potential to be a life-saver for those with iron overload, it is crucial to keep a watchful eye on kidney function to avoid this serious side effect.

Monitoring Kidney Function: A Crucial Desert Oasis

The study underscores the importance of regular kidney function tests for patients on deferasirox, even if they don't have any symptoms. Early detection of kidney problems, like spotting a small crack in the oasis wall, is essential to prevent further damage.

Protecting Your Kidney Oasis: Staying Hydrated and Informed

If you're taking deferasirox, it's essential to talk to your doctor about the risk of Fanconi syndrome. They can help you understand the importance of regular checkups and answer any questions you may have. Remember, staying informed, like navigating a desert with a reliable guide, is key to keeping your health oasis thriving.

Dr.Camel's Conclusion

Deferasirox is a vital tool in managing iron overload, but it’s crucial to be aware of the potential for kidney complications. Just like a traveler in the desert must carefully conserve water, patients on deferasirox must monitor their kidney function to ensure their health oasis remains strong.

Date :
  1. Date Completed 2021-10-15
  2. Date Revised 2021-10-15
Further Info :

Pubmed ID

33529394

DOI: Digital Object Identifier

10.1111/vox.13064

Related Literature

SNS
PICO Info
in preparation
Languages

English

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