Intralesional 5-Fluorouracil for Treatment of Non-Melanoma Skin Cancer: A Systematic Review.

Author: KuraitisDrew, MaghfourJalal, MurinaAndrea

Paper Details 
Original Abstract of the Article :
BACKGROUND: Surgical excision is the paradigm treatment option for non-melanoma skin cancer (NMSC), however intralesional fluorouracil (IL 5-FU) is an efficacious alternative and superior to other chemotherapy agents in NMSC. Yet, little summative data exists on the topic. OBJECTIVE: To assess the ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.36849/JDD.5518

データ提供:米国国立医学図書館(NLM)

Intralesional 5-Fluorouracil for Non-Melanoma Skin Cancer

The field of dermatology constantly seeks effective and minimally invasive treatments for non-melanoma skin cancer (NMSC). Surgical excision is a common approach, but intralesional fluorouracil (IL 5-FU) offers a potential alternative, especially for cases that are not amenable to surgery. This study, focusing on dermatologic oncology, systematically reviews the efficacy of IL 5-FU in treating NMSC.

IL 5-FU's Efficacy in Treating NMSC

The study, a systematic review of published research, found that IL 5-FU demonstrated higher clearance rates for squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) compared to keratoacanthoma (KA). However, it's important to note that the majority of data came from individual case reports, suggesting a need for larger studies to confirm these findings. The research underscores the potential of IL 5-FU as a viable treatment option for NMSC, particularly for SCC and BCC, and highlights the need for further research to establish more definitive evidence.

Choosing the Right Treatment for Skin Cancer

This research provides valuable information about the potential of IL 5-FU as a treatment option for NMSC. It reinforces the importance of individualized treatment plans based on specific tumor characteristics and patient preferences. Consulting a dermatologist is essential for determining the most appropriate treatment approach to ensure the best possible outcomes.

Dr.Camel's Conclusion

Think of it like a camel encountering a prickly cactus in the desert. A wise camel knows to avoid the thorns and seek out a more hospitable source of sustenance. This research reminds us that there are different treatment options available for NMSC, and a careful evaluation of each option is crucial for finding a path that leads to a clear and healthy outcome.

Date :
  1. Date Completed 2021-06-28
  2. Date Revised 2021-06-28
Further Info :

Pubmed ID

33538569

DOI: Digital Object Identifier

10.36849/JDD.5518

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.