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Noninferiority clinical trial comparing the bowel cleansing efficacy of sodium phosphate tablets (Quiklean<sup>&#174;</sup>) with a polyethylene glycol/bisacodyl kit.

Author: ChangSheng-Chi, ChenHung-Chang, ChenJiann-Hwa, ChenWilliam Tzu-Liang, ChenYi-Chang, ChiangHua-Che, HsiaoKoung-Hung, HsiehMing-Hao, HsiehYo-Wen, HungShih-Ya, KeTao-Wei, TsaiYuan-Yao, WangHwei-Ming

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The 32-tablet sodium phosphate bowel cleansing agent (Quiklean) is as effective as the 4-liter polyethylene glycol (PEG) solution in preparing patients for colonoscopy.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Efficient bowel cleansing is essential for a successful colonoscopy, but the ideal cleansing agent, volume, and pharmaceutical dosage form have yet to be determined. Small-volume cleansers enhance patient compliance. AIM: To compare the bowel cleansing efficacy of 32-tablet sodium phosp...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856840/

データ提供：米国国立医学図書館（NLM）

Sodium Phosphate Tablets: A Quick and Efficient Bowel Cleanser

This study compares the bowel cleansing efficacy of sodium phosphate tablets (Quiklean®) to a polyethylene glycol/bisacodyl kit, both commonly used for colonoscopy preparation. The research team conducted a multicenter, randomized, noninferiority trial involving 472 outpatients scheduled for colonoscopy. The results indicate that sodium phosphate tablets demonstrated noninferior bowel cleansing efficacy compared to the polyethylene glycol/bisacodyl kit, with a significantly higher success rate (98.6% vs 89.5%). The study also highlighted the convenience and patient acceptability of sodium phosphate tablets, suggesting that they could be a valuable alternative for colonoscopy preparation.

Sodium Phosphate Tablets: A Speedy Desert Oasis

This research highlights the benefits of sodium phosphate tablets for colonoscopy preparation, comparing them to a quick and efficient desert oasis offering essential hydration and refreshment. Sodium phosphate tablets, like this oasis, provide a convenient and effective solution for bowel cleansing, ensuring a smooth and successful colonoscopy experience.

A Smoother Journey to Colonoscopy

This study presents a valuable option for patients undergoing colonoscopy, highlighting the efficacy and convenience of sodium phosphate tablets. Imagine a camel caravan equipped with a portable water source, ensuring a comfortable and efficient journey through the desert – sodium phosphate tablets, like this portable source, can help navigate the preparation process for colonoscopy, leading to a more positive and manageable experience.

Dr.Camel's Conclusion

This study underscores the value of sodium phosphate tablets for colonoscopy preparation. Like a well-stocked oasis in a vast desert, these tablets offer a convenient and effective solution for bowel cleansing, ensuring a smoother and more successful colonoscopy experience for patients.
Date :
  1. Date Completed 2021-05-14
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

33584074

DOI: Digital Object Identifier

PMC7856840

Related Literature

Article Analysis
・Effective treatment of colon cleansing
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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