Rasagiline effects on glucose metabolism, cognition, and tau in Alzheimer's dementia.

Author: AndrewsRandolph D, CummingsJeffrey, FeldmanHoward H, FillitHoward, KinneyJefferson W, LeverenzJames B, LukicAna S, MatthewsDawn C, RevtaCarolyn, RitterAaron, ThomasRonald G, TousiBabak, ZhongKate

Paper Details 
Original Abstract of the Article :
A Phase II proof of concept (POC) randomized clinical trial was conducted to evaluate the effects of rasagiline, a monoamine oxidase B (MAO-B) inhibitor approved for Parkinson disease, in mild to moderate Alzheimer's disease (AD). The primary objective was to determine if 1 mg of rasagiline daily fo...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882538/

データ提供:米国国立医学図書館(NLM)

Rasagiline: A Potential Oasis in the Desert of Alzheimer's Disease

The world of [Alzheimer's disease (AD)] research is constantly searching for new treatments to slow disease progression and improve cognitive function. This Phase II clinical trial investigates the effects of [rasagiline], a [monoamine oxidase B (MAO-B) inhibitor], in patients with AD. Imagine a camel traversing a desert landscape, its senses heightened by the journey – that's how rasagiline might work, potentially enhancing brain function and slowing the progression of AD.

Rasagiline: A Multifaceted Approach to Alzheimer's Treatment

The study examined the effects of rasagiline on [glucose metabolism], [cognition], and [tau] in patients with AD. While further research is needed to confirm these findings, the study provides encouraging evidence for the potential of rasagiline in treating AD. It suggests that rasagiline might not only improve cognition but also influence brain metabolism and tau levels, potential targets for AD therapy.

A Promising Pathway for Alzheimer's Treatment: Improving Cognitive Function and Brain Health

This research offers hope for individuals with AD and their families, highlighting the potential of rasagiline as a promising treatment option. While further research is needed to fully understand the long-term effects of rasagiline, the study's findings encourage continued exploration of this drug and its potential to improve the lives of those affected by Alzheimer's disease.

Dr.Camel's Conclusion

Just as a camel relies on its keen senses to navigate the desert, Alzheimer's patients struggle to maintain their cognitive abilities. This study offers a glimmer of hope, suggesting that rasagiline might provide a potential oasis in the desert of Alzheimer's disease, improving cognitive function and slowing the progression of this challenging illness.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-04-20
Further Info :

Pubmed ID

33614888

DOI: Digital Object Identifier

PMC7882538

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Languages

English

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