Acute and long-term effects of saxagliptin on post-prandial glycemic response in obese patients with impaired glucose tolerance.

Author: ChihebSabrina, CossonEmmanuel, FysekidisMarinos, RezkiAmel, ValensiPaul, VicautEric

Paper Details 
Original Abstract of the Article :
Dipeptidyl-peptidase inhibitors might be useful in type 2 diabetes prevention. ACCES (ACute and Chronic Effects of Saxagliptin) was a randomized, placebo-controlled, double-blind, controlled phase 2, pilot study aiming to examine in obese patients with impaired glucose tolerance (IGT) the acute effe...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.numecd.2020.12.025

データ提供:米国国立医学図書館(NLM)

Saxagliptin: A New Approach to Managing Postprandial Glycemic Response in Obese Patients with Impaired Glucose Tolerance

Impaired glucose tolerance (IGT) is a precursor to type 2 diabetes, characterized by elevated blood sugar levels after meals. This study examines the acute and long-term effects of saxagliptin, a dipeptidyl-peptidase inhibitor, on postprandial glycemic response in obese patients with IGT. The authors conducted a randomized, placebo-controlled, double-blind trial to evaluate the impact of saxagliptin on glucose levels at fasting and postprandially after a standard breakfast. The study's findings provide valuable insights into the potential of saxagliptin for preventing the progression of IGT to type 2 diabetes.

Saxagliptin: A Potential Tool for Preventing Type 2 Diabetes

The study suggests that saxagliptin may have a beneficial effect on postprandial glycemic response in obese patients with IGT. This suggests that saxagliptin could be a valuable tool for preventing the progression of IGT to type 2 diabetes. The researchers emphasize the importance of further investigation to confirm these findings and explore the long-term implications of saxagliptin use in managing IGT and preventing diabetes.

Managing Blood Sugar: A Multifaceted Approach

If you are diagnosed with IGT or are at risk for type 2 diabetes, it's crucial to adopt a healthy lifestyle that includes regular physical activity, a balanced diet, and weight management. Your healthcare provider can assess your individual needs and recommend appropriate interventions, potentially including medications such as saxagliptin. By taking proactive steps, you can significantly reduce your risk of developing type 2 diabetes and maintain optimal health.

Dr.Camel's Conclusion

The journey to managing blood sugar levels can be like traversing a desert landscape, navigating fluctuating levels and seeking sustainable solutions. This study provides a glimpse into the potential of saxagliptin as a tool for preventing type 2 diabetes, offering a ray of hope for those at risk. As a researcher who has witnessed the impact of diabetes on countless individuals, I am encouraged by the ongoing efforts to develop innovative treatments that can help people achieve better blood sugar control.

Date :
  1. Date Completed 2021-04-05
  2. Date Revised 2021-04-05
Further Info :

Pubmed ID

33618922

DOI: Digital Object Identifier

10.1016/j.numecd.2020.12.025

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.