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Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure: The HENIVOT Randomized Clinical Trial.

Author: , AntonelliMassimo, BelloGiuseppe, BerardiCecilia, BitondoMaria Maddalena, BocciMaria Grazia, BongiovanniFilippo, CarelliSimone, CesaranoMelania, ContiGiorgio, CutuliSalvatore L, De PascaleGennaro, Dell'AnnaAntonio M, Delle CeseLuca, FalòGiulia, GriecoDomenico Luca, MaggioreSalvatore Maurizio, MengaLuca S, MontiniLuca, MontomoliJonathan, NataliniDaniele, PiervincenziEdoardo, PintaudiGabriele, RanieriV Marco, RosàTommaso, SpadaroSavino, TanzarellaEloisa S, TonettiTommaso, VelardoMatteo, VoltaCarlo Alberto

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A multicenter randomized clinical trial of 109 patients with COVID-19 and moderate to severe hypoxemic respiratory failure found that treatment with helmet noninvasive ventilation, compared with high-flow nasal oxygen, resulted in no significant difference in the number of days free of respiratory support within 28 days. However, the rate of endotracheal intubation was significantly lower in the helmet group.
Paper Details　
Original Abstract of the Article :
IMPORTANCE: High-flow nasal oxygen is recommended as initial treatment for acute hypoxemic respiratory failure and is widely applied in patients with COVID-19. OBJECTIVE: To assess whether helmet noninvasive ventilation can increase the days free of respiratory support in patients with COVID-19 com...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995134/

データ提供：米国国立医学図書館（NLM）

Helmet Noninvasive Ventilation vs. High-Flow Nasal Oxygen: A Race Against Time

The COVID-19 pandemic presented an unprecedented challenge to the medical community. This study focuses on the treatment of patients with COVID-19 who are experiencing moderate to severe hypoxemic respiratory failure. The researchers investigated the efficacy of two different noninvasive ventilation methods: helmet noninvasive ventilation and high-flow nasal oxygen. They aimed to determine which method could increase the number of days patients remained free from respiratory support.

Comparing Ventilation Methods in the Face of COVID-19

The study involved 109 patients with COVID-19. The participants were randomly assigned to receive either helmet noninvasive ventilation or high-flow nasal oxygen. The researchers compared the two groups based on the number of days free of respiratory support, the need for endotracheal intubation, and other important outcomes.

The Promise of Helmet Ventilation

While both methods showed promise, the study found that helmet noninvasive ventilation was associated with a lower rate of endotracheal intubation. This suggests that helmet ventilation may be a more effective option for certain patients, particularly those at higher risk of needing invasive mechanical ventilation. However, further research is needed to confirm this finding and understand the long-term implications of each method.

Dr.Camel's Conclusion

Just as a camel relies on its unique adaptations to survive in the harsh desert, COVID-19 patients require specialized medical attention. This study explores the use of different ventilation methods to support patients struggling with respiratory failure. While the results are promising, further research is needed to refine our understanding and develop optimal treatment strategies for COVID-19 patients.

Date :
  1. Date Completed 2021-05-11
  2. Date Revised 2022-01-31
Further Info :

Pubmed ID

33764378

DOI: Digital Object Identifier

PMC7995134

Related Literature

Article Analysis
・Effective treatment of respiratory failure
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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