Sigmoid Sinus Thrombosis Followed by Splenic Infarction Due to Imatinib Therapy in a Patient with Gastrointestinal Stromal Tumor; Hematological Side Effects of Imatinib.

Author: DemirağGüzin, YilmazHatice, YılmazAli

Paper Details 
Original Abstract of the Article :
Imatinib has an important place as an adjuvant therapy as well as in the treatment of metastatic disease caused by gastrointestinal stromal tumor (GIST), which is one of the common mesenchymal tumors of the gastrointestinal tract. Imatinib is a tyrosine kinase inhibitor and is generally well tolerat...See full text at original site
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引用元:
https://doi.org/10.18433/jpps31425

データ提供:米国国立医学図書館(NLM)

Imatinib: A Double-Edged Sword

This case report sheds light on a rare but serious side effect of imatinib, a tyrosine kinase inhibitor used to treat gastrointestinal stromal tumors (GISTs). It's like navigating a treacherous desert landscape, where unexpected dangers can lurk beneath the surface. This case report highlights the importance of careful monitoring for potential complications associated with this medication, particularly in patients with GIST.

The patient in this case experienced sigmoid sinus thrombosis followed by splenic infarction, highlighting the potential for serious thrombotic events associated with imatinib. It's like encountering a hidden crevice in the desert, where a seemingly innocuous path can lead to unforeseen consequences. The researchers emphasize the importance of considering these rare but potentially life-threatening complications in patients treated with imatinib, particularly those presenting with headache or abdominal pain.

Navigating the Desert of GIST Treatment

This case report serves as a reminder of the complex nature of GIST treatment, highlighting the potential for both benefits and risks associated with imatinib therapy. It's like navigating a vast desert, where careful observation and vigilance are crucial for ensuring a safe and successful journey.

Monitoring for Safety

This case report underscores the importance of careful monitoring for potential complications in patients treated with imatinib. It's like keeping a watchful eye for hidden dangers in a desert environment, ensuring safety and well-being. By staying vigilant and responding promptly, we can minimize the risks associated with this medication and maximize its potential benefits.

Dr.Camel's Conclusion

This case report serves as a cautionary tale about the potential for serious side effects associated with imatinib therapy. It's like discovering a hidden danger in a seemingly safe desert oasis, reminding us to stay alert and be prepared for unexpected challenges. By being aware of these potential complications and practicing careful monitoring, we can ensure the safety and well-being of our patients while maximizing the benefits of this important medication.

Date :
  1. Date Completed 2021-10-26
  2. Date Revised 2021-10-26
Further Info :

Pubmed ID

33784493

DOI: Digital Object Identifier

10.18433/jpps31425

Related Literature

SNS
PICO Info
in preparation
Languages

English

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