Paper Details 
Original Abstract of the Article :
Farnesoid X receptor (FXR) agonist obeticholic acid (OCA) has emerged as a potential therapy for nonalcoholic fatty liver disease (NAFLD). However, the side effects of OCA may limit its application in clinics. We identified previously that isotschimgine (ITG) is a non-steroidal FXR selective agonist...See full text at original site
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引用元:
https://doi.org/10.1002/ptr.7055

データ提供:米国国立医学図書館(NLM)

Isotschimgine: A Promising New Therapy for Nonalcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH) is a growing health concern, often leading to liver fibrosis and cirrhosis. This research investigates the therapeutic potential of isotschimgine (ITG), a non-steroidal Farnesoid X receptor (FXR) agonist, for the treatment of NASH and fibrosis. The researchers found that ITG effectively reduced liver steatosis, inflammation, and fibrosis in animal models, suggesting its potential as a novel therapy for NASH and related liver diseases.

Isotschimgine: Targeting FXR for Liver Health

Imagine a desert oasis with a hidden spring, providing vital water for surrounding life. Isotschimgine acts like that hidden spring, activating FXR and promoting liver health. This research highlights the therapeutic potential of ITG, a non-steroidal FXR agonist, for the treatment of NASH and fibrosis, offering hope for individuals battling these challenging liver diseases.

A New Oasis for Liver Health: Isotschimgine's Potential Benefits

This study suggests that ITG might offer a new and effective treatment option for NASH and fibrosis, offering a ray of hope for those struggling with these debilitating liver diseases. It's like discovering a new oasis in the desert, providing a source of relief and healing for those in need.

Dr. Camel's Conclusion

This research reminds me of the power of nature's bounty, where even in the harshest environments, there are hidden treasures waiting to be discovered. Isotschimgine, like a precious desert herb, holds promise for improving liver health and offers hope for a brighter future for those affected by NASH and fibrosis.

Date :
  1. Date Completed 2021-06-29
  2. Date Revised 2021-06-29
Further Info :

Pubmed ID

33784797

DOI: Digital Object Identifier

10.1002/ptr.7055

Related Literature

SNS
PICO Info
in preparation
Languages

English

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