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The pediatric psychopharmacology of autism spectrum disorder: A systematic review - Part I: The past and the present.

Author: ArangoCelso, BrognaClaudia, CucinottaFrancesca, LambertiMarco, PersicoAntonio M, RicciardelloArianna, TurrizianiLaura, VitielloBenedetto

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Autism spectrum disorder (ASD) affects many children and adults, causing challenges with social skills, communication, behavior, and sensory processing. While there are no medications that directly treat these core symptoms, some medications can help with specific problems. For example, atypical antipsychotics can help with hyperactivity and aggression, antidepressants can reduce repetitive behaviors and irritability, and stimulants can improve attention and focus in children with both ASD and ADHD. More research is needed to develop better treatments for ASD, including identifying ways to predict how individuals will respond to medication and finding drugs that directly address core autism symptoms.
Paper Details　
Original Abstract of the Article :
Autism Spectrum Disorder (ASD) is a severe and lifelong neurodevelopmental disorder, with high social costs and a dramatic burden on the quality of life of patients and family members. Despite its high prevalence, reaching 1/54 children and 1/45 adults in the United States, no pharmacological treatm...See full text at original site
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引用元：
https://doi.org/10.1016/j.pnpbp.2021.110326

データ提供：米国国立医学図書館（NLM）

The Pediatric Psychopharmacology of Autism Spectrum Disorder: A Comprehensive Review

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder that presents significant challenges for children and their families. This research offers a comprehensive review of the current state of psychopharmacological therapy for ASD in children and adolescents. The authors provide an overview of the available medications, their efficacy, and potential side effects. They highlight the challenges of treating core ASD symptoms with medication and emphasize the need for further research to develop more targeted therapies. This review serves as a valuable resource for clinicians navigating the complex landscape of ASD treatment.

Navigating the Complexities of ASD Treatment: A Multifaceted Approach

This research underscores the complexities of treating ASD, highlighting the need for a multifaceted approach that combines medication, behavioral therapies, and supportive services. The authors emphasize the importance of individualized treatment plans, tailored to the specific needs of each child. They also acknowledge the limitations of current medications and the need for ongoing research to develop more effective therapies.

The Search for Solutions: A Journey Towards More Effective Therapies

This research serves as a reminder of the ongoing search for more effective therapies for ASD. The authors highlight the need for further research to develop medications that directly target core ASD symptoms and to identify biomarkers that can predict individual responses to treatment. The quest for solutions continues, driven by the desire to improve the lives of children with ASD and their families.

Dr.Camel's Conclusion

Just as a desert traveler seeks a clear path through the shifting sands, clinicians seeking to treat ASD navigate a complex landscape of challenges and possibilities. This research offers a comprehensive guide to the current state of psychopharmacological therapy for ASD, highlighting the need for continued research and a personalized approach to treatment.

Date :
  1. Date Completed 2022-02-11
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

33857522

DOI: Digital Object Identifier

10.1016/j.pnpbp.2021.110326

SNS
PICO Info
in preparation
Languages

English

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