Disposition of posaconazole after single oral administration in large falcons (Falco spp): Effect of meal and dosage and a non-compartmental model to predict effective dosage.

Author: AzmanisPanagiotis, NaidooVinny, PappalardoLucia, SaraZiad A J, SilvanoseChristudas

Paper Details 
Original Abstract of the Article :
Posaconazole has been used anecdotally to treat aspergillosis in falcons resistant to voriconazole. In human medicine, it is used prophylactically in immunosuppressed human subjects with invasive pulmonary aspergillosis. So far, no studies have been performed in birds. The aim of this study was to e...See full text at original site
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引用元:
https://doi.org/10.1093/mmy/myab019

データ提供:米国国立医学図書館(NLM)

Posaconazole: A Potential Oasis in the Desert of Aspergillosis Treatment?

The desert of medicine is full of challenges, and treating fungal infections like aspergillosis is no exception. This study focused on posaconazole, an antifungal drug that's typically used in humans. The researchers, like explorers venturing into a new territory, investigated the use of posaconazole in falcons, large birds of prey that are known to suffer from aspergillosis.

They explored the pharmacokinetic behavior of posaconazole in falcons, taking into account factors like food intake and dosage. This research is like studying the effects of different types of desert plants on a specific type of animal. The results suggest that posaconazole could be a potential treatment option for aspergillosis in falcons.

Finding New Solutions in the Desert

The study highlights the potential of repurposing drugs, like finding new uses for existing desert plants. It suggests that posaconazole, originally developed for humans, could be effective in treating aspergillosis in falcons.

Navigating the Desert of Aspergillosis Treatment

The study is an important step in finding new solutions for treating aspergillosis in falcons. This research, like finding a new oasis in the desert, offers hope for these majestic birds.

Dr.Camel's Conclusion

The study on posaconazole in falcons is a promising step towards finding new treatments for aspergillosis in these birds. It reminds us that the desert of medicine is full of possibilities, and we should continue to explore new avenues for treating diseases.

Date :
  1. Date Completed 2021-11-22
  2. Date Revised 2021-11-22
Further Info :

Pubmed ID

33891699

DOI: Digital Object Identifier

10.1093/mmy/myab019

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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