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Continuous-Infusion Foscarnet Facilitates Administration in Hematopoietic Stem Cell Transplantation Patients.
Author: BrownJanice Wes, DomingoWalter, JohnsrudJoyce J, NguyenIsabelle T
Original Abstract of the Article :
Infections due to herpesviruses resistant to first-line antivirals remains an ever-present and serious complication in recipients of hematopoietic cell transplantation (HCT) and other cellular therapies. Foscarnet is the most common therapy for patients who have resistant herpesvirus infections or i...See full text at original site
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引用元:
https://doi.org/10.1016/j.jtct.2021.03.018
データ提供:米国国立医学図書館(NLM)
Continuous-Infusion Foscarnet for Hematopoietic Stem Cell Transplant Patients
The field of [hematopoietic stem cell transplantation (HCT)] is constantly evolving to address the challenges of [herpesvirus infections], which can be a real thorn in the side for these patients. This research delves into the administration of [foscarnet], a powerful antiviral, and its impact on [nephrotoxicity] in HCT recipients. The researchers used a [retrospective, single-center, observational study] to compare the effectiveness and safety of [continuous-infusion foscarnet] with [intermittent infusion] in a group of HCT patients. Their findings suggest that both methods have similar rates of adverse reactions, most notably [acute kidney injury (AKI)], which is like a camel getting a little bit thirsty in the desert. They discovered that continuous infusion is a feasible option, which could make treatment more convenient for patients.
Continuous Infusion: A Feasible Option for Outpatient Treatment
The study's results suggest that continuous infusion is a viable alternative to intermittent infusion. This finding could be beneficial for patients, especially those who receive treatment in an outpatient setting. It could also lead to a decrease in hospital stays, which can be a real blessing for those who are already feeling overwhelmed by their condition.
The Importance of Careful Monitoring
While the researchers found that both methods had similar rates of AKI, it is important to remember that this is a serious side effect. As a wise camel, I always say, it's crucial to be aware of potential complications and to closely monitor your health. If you are receiving foscarnet treatment, you should be aware of the potential for AKI, and you should discuss any concerns you have with your doctor.
Dr.Camel's Conclusion
This research provides valuable insights into the administration of foscarnet in HCT patients. It suggests that continuous infusion could be a beneficial alternative to intermittent infusion, and it highlights the importance of careful monitoring for AKI.
Date :
- Date Completed 2021-07-15
- Date Revised 2021-07-15
Further Info :
Related Literature
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