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In vitro cytotoxic effect of a chitin-like polysaccharide produced by Mortierella alpina on adrenocortical carcinoma cells H295R, and its use as mitotane adjuvant.
Author: BonattoSandro J R, Goyzueta MamaniLuis Daniel, SoccolCarlos Ricardo, TanobeValcineide A O, de CarvalhoJúlio Cesar
Original Abstract of the Article :
This study presents an in vitro evaluation of the antitumor potential of a chitin-like exopolysaccharide (EPS, produced by Mortierella alpina) on Adrenocortical carcinoma cells (ACC) compared to mitotane, a commercial drug commonly used in ACC treatment, and known for its side effects. Techniques of...See full text at original site
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引用元:
https://doi.org/10.1007/s11626-021-00560-y
データ提供:米国国立医学図書館(NLM)
Conquering Adrenocortical Carcinoma: A Quest for New Weapons
Adrenocortical carcinoma, like a hidden predator lurking in the desert sands, is a formidable foe in the fight against cancer. This research explores the potential of a chitin-like exopolysaccharide (EPS) as a new weapon in the arsenal against this disease. The study investigates the cytotoxic effects of EPS on adrenocortical carcinoma cells, comparing its effectiveness to mitotane, a standard treatment known for its side effects. The findings suggest that EPS may offer a promising alternative, potentially providing a more effective and less toxic treatment approach, like a skilled warrior wielding a new and powerful weapon.
Seeking a New Equilibrium
The research reveals that EPS exhibits significant cytotoxic effects on adrenocortical carcinoma cells, demonstrating its potential to fight this type of cancer. The study found that EPS is comparable to mitotane in its effectiveness, potentially providing a safer and more tolerable treatment option. The research also explores the possibility of combining EPS with mitotane at lower doses, suggesting a potential synergistic effect that could further enhance treatment efficacy, like a camel caravan drawing strength from multiple resources.
Hope for a Brighter Future
The research offers a glimmer of hope for patients battling adrenocortical carcinoma. The potential of EPS as a new treatment option suggests that there may be safer and more effective ways to combat this disease. The study's findings, like a well-hidden oasis discovered by a weary traveler, provide a beacon of hope for those seeking new treatment options and a better quality of life.
Dr. Camel's Conclusion
This research explores the potential of a chitin-like exopolysaccharide (EPS) as a new weapon in the fight against adrenocortical carcinoma. The study's findings offer a promising alternative to current treatments, potentially providing a safer and more effective approach. The research highlights the importance of continued exploration and innovation in the search for new cancer treatments.
Date :
- Date Completed 2021-12-03
- Date Revised 2021-12-14
Further Info :
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