Efficacy of elobixibat as bowel preparation agent for colonoscopy: Prospective, randomized, multi-center study.

Author: AkutagawaTakashi, EsakiMotohiro, HidakaHidenori, JubashiAmane, KawakuboHiroharu, MatsunagaTakuya, MiyaharaKoichi, NodaTakahiro, OgataShinichi, SakataYasuhisa, ShimodaRyo, TakamoriAyako, TakeuchiYuki, TanakaYuichiro, TominagaNaoyuki, TsunadaSeiji, TsuruokaNanae, YamaguchiDaisuke

Paper Details 
Original Abstract of the Article :
Elobixibat is a novel ileal bile acid transporter inhibitor. This study aimed to compare the efficacy, tolerability, and safety of the combination of elobixibat and 1 L of polyethylene glycol formulation containing ascorbic acid (PEG-Asc) solution versus the combination of sodium picosulfate and 1-L...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290049/

データ提供:米国国立医学図書館(NLM)

Preparing for the Journey: Elobixibat for Colonoscopy

Colonoscopy, a crucial diagnostic and screening tool for colorectal cancer, requires thorough bowel preparation to ensure optimal visualization. This study compares the efficacy and safety of two bowel preparation regimens: elobixibat combined with polyethylene glycol formulation containing ascorbic acid (PEG-Asc) and sodium picosulfate combined with PEG-Asc. The study aims to determine the best preparation for colonoscopy, ensuring clear visualization of the colon while minimizing patient discomfort.

Finding the Right Route: Elobixibat Shows Promise

The study found that elobixibat, a novel ileal bile acid transporter inhibitor, combined with PEG-Asc provided effective bowel preparation for colonoscopy, comparable to sodium picosulfate combined with PEG-Asc. Elobixibat, with its unique mechanism of action, offers a potential alternative to traditional bowel preparation agents.

Optimizing Colonoscopy: A More Comfortable Experience

The study's findings suggest that elobixibat could contribute to a more effective and potentially more comfortable bowel preparation experience for patients undergoing colonoscopy. Further research could explore the long-term implications of elobixibat and its potential to improve patient outcomes.

Dr.Camel's Conclusion

This study explores the potential of elobixibat as a novel bowel preparation agent for colonoscopy, offering a promising alternative to traditional methods. Further research is needed to validate these findings and explore the long-term benefits of this approach.

Date :
  1. Date Completed 2022-01-13
  2. Date Revised 2022-07-21
Further Info :

Pubmed ID

33971037

DOI: Digital Object Identifier

PMC9290049

Related Literature

SNS
PICO Info
in preparation
Languages

English

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