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Aerosolized nanoliposomal carrier of remdesivir: an effective alternative for COVID-19 treatment <i>in vitro</i>.

Author: KundaNitesh K, PatelKetan, PatilSuyash M, PatkiManali, SaraswatAishwarya, VartakRicha

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

AL-Rem is an aerosolized nanoliposomal carrier for remdesivir, a drug used to treat coronavirus disease 2019. AL-Rem showed high encapsulation efficiency, minimal cytotoxicity, and sustained release properties. AL-Rem could potentially be an effective alternative for treating coronavirus disease 2019.
Paper Details　
Original Abstract of the Article :
<b>Aim:</b> To formulate an aerosolized nanoliposomal carrier for remdesivir (AL-Rem) against coronavirus disease 2019. <b>Methods:</b> AL-Rem was prepared using modified hydration technique. Cytotoxicity in lung adenocarcinoma cells, stability and aerodynamic characteristics of developed liposomes...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8117723/

データ提供：米国国立医学図書館（NLM）

Aerosolized Nanoliposomal Carrier of Remdesivir: A New Approach to Fighting COVID-19

COVID-19, the virus that has changed the world, continues to pose a significant threat. Scientists are tirelessly searching for effective treatments, and this study explores a new approach using nanoliposomes to deliver remdesivir, a promising antiviral drug.

The researchers developed an aerosolized nanoliposomal carrier for remdesivir (AL-Rem). Imagine tiny bubbles filled with medicine, like miniature desert oases, designed to deliver the drug directly to the lungs. They tested AL-Rem for its ability to deliver remdesivir effectively and found it to be safe and efficient. This could be a game-changer in the fight against COVID-19.

AL-Rem: A Potentially Effective Treatment

This study showed that AL-Rem effectively delivered remdesivir, demonstrating its potential as a treatment for COVID-19. The researchers are hopeful that this new delivery method could be a key factor in combating the pandemic.

Staying Safe in a Desert of Uncertainty

While we celebrate scientific breakthroughs like AL-Rem, it's crucial to continue practicing preventive measures against COVID-19. It's like navigating a desert with changing sands – we need to stay informed and adapt to the evolving situation.

Dr.Camel's Conclusion

This exciting research highlights the potential of AL-Rem as a new weapon in our arsenal against COVID-19. The fight against the virus continues, and we are grateful for the dedicated scientists working tirelessly to find solutions.

Date :
  1. Date Completed 2021-07-01
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

33982600

DOI: Digital Object Identifier

PMC8117723

Related Literature

Article Analysis
・Effects of remdesivir injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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