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Anti-amiodarone antibodies: detection and relationship to the development of side effects.

Author: PichlerW J, SchindlerL, StadlerB M, StäubliM, de WeckA L

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

An immunodot technique was developed for detecting anti-amiodarone antibodies, potentially contributing to the understanding of amiodarone-induced side effects.
Paper Details　
Original Abstract of the Article :
It has become evident in the past few years that amiodarone, a powerful antiarrhythmic agent, induces considerable side effects. These may be due to an amiodarone-elicited lipid storage disease and to the iodine content of amiodarone, but might also be causally related to amiodarone-induced immune r...See full text at original site
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引用元：
https://doi.org/10.1016/s0002-9343(88)80342-5

データ提供：米国国立医学図書館（NLM）

Amiodarone Antibodies: A Desert of Immune Reactions

Amiodarone is a powerful medication used to treat irregular heartbeats. This study explores the role of amiodarone-induced immune reactions in causing side effects. Imagine a desert where an unexpected storm of antibodies can disrupt the delicate balance of health. The researchers developed a sensitive assay to detect anti-amiodarone antibodies, which are antibodies that target the drug itself. They found that the presence of these antibodies was associated with the development of side effects, highlighting the potential for immune-mediated reactions to contribute to the adverse effects of amiodarone.

Understanding Immune Reactions to Amiodarone

This study sheds light on the potential for amiodarone-induced immune reactions to contribute to side effects. It's like uncovering a hidden oasis of immune activity in a desert landscape. Understanding these reactions could lead to more targeted therapies and better management of amiodarone-related adverse events, improving patient safety and well-being.

Taking Amiodarone: A Camel's Advice

If you are taking amiodarone, it's important to be aware of the potential for side effects. It's like navigating a desert where unexpected storms can arise. Talk to your doctor about any concerns you may have and monitor your health closely. Early detection of potential complications can lead to more effective management and better outcomes.

Dr.Camel's Conclusion

This study emphasizes the importance of understanding the role of immune reactions in the development of amiodarone-related side effects. It's a reminder that even in the seemingly barren desert of medical knowledge, there are always new discoveries to be made.

Date :
  1. Date Completed 1988-09-02
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

3400695

DOI: Digital Object Identifier

10.1016/s0002-9343(88)80342-5

Related Literature

Article Analysis
・Side Effects of amiodarone
SNS
PICO Info
in preparation
Languages

English

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