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Efficacy of phenobarbital in treating elderly epilepsy patients in rural northeast China: A community-based intervention trial.

Author: LiJing, LiNan, LinWeihong, ZhaoDanyang

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Elderly epilepsy patients had a good response to PB monotherapy. Early-onset epilepsy patients complained of more serious adverse events, while late-onset epilepsy patients were more prone to withdrawal due to side effects. The commonest cause of drug withdrawal was nonadherence, with early-onset epilepsy patients surviving longer than late-onset patients.
Paper Details　
Original Abstract of the Article :
OBJECT: To provide information on the characteristics of elderly epilepsy patients in rural Northeast China. METHOD: Consecutive patients (aged >60) who were diagnosed with convulsive epilepsy in seven counties in Jilin Province, Northeast China, between January 2010 and December 2019 were included...See full text at original site
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引用元：
https://doi.org/10.1016/j.seizure.2021.05.006

データ提供：米国国立医学図書館（NLM）

Phenobarbital: A Valuable Treatment for Epilepsy in Rural China

This study investigates the effectiveness of phenobarbital (PB) in treating elderly epilepsy patients in rural Northeast China. Epilepsy is a common neurological disorder characterized by recurrent seizures. This research focused on the characteristics, treatment responses, and survival outcomes of elderly epilepsy patients in a specific region of China.

Phenobarbital's Effectiveness in Rural China

The study found that PB monotherapy was effective in controlling seizures in elderly epilepsy patients. There was no significant difference in treatment response between patients with early-onset epilepsy and late-onset epilepsy. However, the study also highlighted challenges related to medication adherence and the occurrence of adverse events.

Addressing Epilepsy in Rural Communities

The research underscores the importance of providing accessible and effective treatment for epilepsy in rural settings. It emphasizes the need for comprehensive patient education and support to enhance medication adherence and improve overall care.

Dr. Camel's Conclusion

Imagine a camel venturing through a vast desert, seeking a safe and reliable source of water. Phenobarbital, for epilepsy patients in rural China, acts like a dependable well, providing relief from seizures and offering a path to improved health. This research highlights the importance of providing accessible and effective treatments in underserved areas.
Date :
  1. Date Completed 2021-07-28
  2. Date Revised 2021-07-28
Further Info :

Pubmed ID

34034063

DOI: Digital Object Identifier

10.1016/j.seizure.2021.05.006

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Article Analysis
・Side Effects of phenobarbital
SNS
PICO Info
in preparation
Languages

English

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