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The High Potency of Green Synthesized Copper Nanoparticles to Prevent the Toxoplasma gondii Infection in Mice.

Author: AlanaziAbdullah D, AlbalawiAishah E, AlyousifMohamed S, EbrahimiKatrin, MahmoudvandHossein, NiaziMassumeh, SepahvandAzadeh

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluates the prophylactic effects of copper nanoparticles (CuNPs) green synthesized by Capparis spinosa fruit methanolic extract alone and combined with atovaquone against chronic toxoplasmosis in mice.
Paper Details　
Original Abstract of the Article :
Nowadays, due to the lack of an effective vaccine to prevent the toxoplasmosis, chemotherapy with the combination of pyrimethamine and sulfadiazine is considered as the "gold standard" treatment for toxoplasmosis. Recent reports have exhibited that these synthesized chemical drugs are associated wit...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s11686-021-00421-4

データ提供：米国国立医学図書館（NLM）

Green Synthesized Copper Nanoparticles: A Promising Approach to Preventing Toxoplasmosis

Toxoplasmosis, a parasitic infection caused by Toxoplasma gondii, poses a significant health threat. This research explores the potential of green synthesized copper nanoparticles (CuNPs) as a prophylactic agent against toxoplasmosis. The authors investigate the effects of CuNPs, alone and in combination with atovaquone, on the progression of chronic toxoplasmosis in mice. Their findings suggest that CuNPs may offer a promising alternative or adjunct to conventional therapies for preventing toxoplasmosis.

Green Nanotechnology: A New Frontier for Parasitic Disease Prevention

The study revealed that green synthesized CuNPs exhibited significant prophylactic activity against chronic toxoplasmosis in mice. The authors observed a reduction in brain tissue cysts and an increase in immune response markers, suggesting that CuNPs may offer a promising approach to preventing toxoplasmosis.

Seeking Safer and More Effective Therapies

As a camel, I’ve learned that the desert holds both challenges and opportunities. This research highlights the potential of green nanotechnology to address the challenges of parasitic diseases like toxoplasmosis. By exploring alternative and potentially safer approaches, we can work towards developing more effective therapies for these infectious diseases.

Dr.Camel's Conclusion

This research offers promising evidence for the use of green synthesized copper nanoparticles as a prophylactic agent against toxoplasmosis. It highlights the potential of green nanotechnology as a new frontier for developing safe and effective therapies for parasitic diseases. Further research is needed to confirm the long-term efficacy and safety of CuNPs in humans.

Date :
  1. Date Completed 2021-12-03
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

34050875

DOI: Digital Object Identifier

10.1007/s11686-021-00421-4

SNS
PICO Info
in preparation
Languages

English

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