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Emerging Molecular Receptors for the Specific-Target Delivery of Ruthenium and Gold Complexes into Cancer Cells.

Author: CorreiaJoão D G, MachadoJoão Franco, MoraisTânia S

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review article focuses on the development of target-specific ruthenium and gold complexes as potential anticancer agents. These metals offer an alternative to platinum-based drugs, which often have severe side effects and can lead to chemoresistance. The review explores the use of these metals in conjunction with biomolecules to target specific membrane proteins, receptors, and even cell organelles like mitochondria.
Paper Details　
Original Abstract of the Article :
Cisplatin and derivatives are highly effective in the treatment of a wide range of cancer types; however, these metallodrugs display low selectivity, leading to severe side effects. Additionally, their administration often results in the development of chemoresistance, which ultimately results in th...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197480/

データ提供：米国国立医学図書館（NLM）

Targeting Cancer Cells with Precision: Exploring the Potential of Ruthenium and Gold Complexes

This research explores the use of ruthenium and gold complexes as potential therapeutic agents for cancer treatment. The study focuses on the development of targeted delivery strategies for these metal complexes, aiming to improve their selectivity and reduce side effects. The authors highlight the importance of targeting specific molecular receptors within cancer cells to enhance the efficacy and safety of these promising anticancer agents.

Navigating the Desert of Cancer Treatment

This research ventures into the challenging landscape of cancer treatment, seeking more precise and effective therapeutic approaches. The study explores the potential of ruthenium and gold complexes, highlighting the importance of targeted delivery strategies to enhance their anticancer activity and minimize side effects. Just as a camel navigating the desert seeks out the most efficient routes, researchers are exploring new pathways to combat cancer.

A Desert Oasis of Targeted Therapy

This research offers a glimmer of hope in the fight against cancer, suggesting a potential new approach based on targeted delivery of ruthenium and gold complexes. The study highlights the importance of precision medicine in cancer treatment, aiming to improve therapeutic outcomes while minimizing side effects. This research is a reminder that the pursuit of effective cancer therapies is a continuous journey, much like a camel's trek across the vast and unpredictable desert, seeking out the most promising oases.

Dr. Camel's Conclusion

This research explores the promising potential of ruthenium and gold complexes as targeted anticancer agents. The study highlights the importance of developing precise delivery strategies to enhance the efficacy and safety of these metal complexes. This research showcases the power of scientific innovation in developing new and effective therapies for cancer. Like a camel navigating the challenging landscape of the desert, researchers are constantly seeking out new paths to combat this formidable foe.
Date :
  1. Date Completed 2021-07-07
  2. Date Revised 2021-07-07
Further Info :

Pubmed ID

34070457

DOI: Digital Object Identifier

PMC8197480

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Languages

English

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