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Triglyceride-Rich Lipoproteins, Apolipoproteins, and Atherosclerotic Cardiovascular Events Among Patients with Diabetes Mellitus and End-Stage Renal Disease on Hemodialysis.

Author: DrechslerChristiane, KatzRonit, Lamprea-MontealegreJulio A, MärzWinfried, ScharnaglHubert, SilbernagelGünther, WannerCristoph, de BoerIan H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This post-hoc analysis examined the association of triglycerides, very-low density lipoprotein cholesterol (VLDL-C), and apolipoproteins B and C-III with atherosclerotic cardiovascular disease (ASCVD) events in patients with type 2 diabetes and end-stage renal disease (ESRD). No evidence was found to support an association between these lipid parameters and ASCVD risk in this population.
Paper Details　
Original Abstract of the Article :
Hypertriglyceridemia may be implicated in the high atherosclerotic cardiovascular disease (ASCVD) risk experienced by patients with end-stage renal disease (ESRD). In this post-hoc analysis of the "Die Deutsche Diabetes Dialyse Studie (4D)" clinical trial, we examined incident ASCVD events, defined ...See full text at original site
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引用元：
https://doi.org/10.1016/j.amjcard.2021.04.023

データ提供：米国国立医学図書館（NLM）

The Desert of Diabetes and Dialysis: Understanding Cardiovascular Risk

Diabetes and end-stage renal disease on hemodialysis are like a particularly harsh desert, where the body faces a range of health challenges. This study focuses on the connection between hypertriglyceridemia, high levels of triglycerides in the blood, and cardiovascular risk in this population.

Exploring the Link Between Triglycerides and Cardiovascular Events

The researchers examined the relationship between triglyceride levels and the occurrence of cardiovascular events, such as heart attacks, strokes, and coronary revascularization procedures. It's like looking for patterns in the desert, searching for a link between a specific feature of the landscape (high triglycerides) and the occurrence of sandstorms (cardiovascular events).

No Clear Connection Found

Surprisingly, the study found no clear evidence that high triglyceride levels increased the risk of cardiovascular events in patients with diabetes and ESRD on hemodialysis. It's like discovering that a certain type of sand dune isn't actually a precursor to sandstorms, as was previously believed.

Dr. Camel's Conclusion

This research adds to our understanding of cardiovascular risk factors in patients with diabetes and ESRD on hemodialysis. It emphasizes the need for ongoing research to fully understand the complex interplay of risk factors and develop effective strategies for preventing cardiovascular events in this vulnerable population. It's like navigating a vast and complex desert, where each new discovery helps us map a path towards better health and wellbeing.
Date :
  1. Date Completed 2021-09-13
  2. Date Revised 2021-09-13
Further Info :

Pubmed ID

34108090

DOI: Digital Object Identifier

10.1016/j.amjcard.2021.04.023

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Languages

English

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