Paper Details 
Original Abstract of the Article :
One strategy to address hyperprolactinemia and associated sexual side effects in patients receiving antipsychotics is switching to an antipsychotic not associated with prolactin elevation (eg, aripiprazole). This post hoc analysis assessed prolactin concentrations and sexual side effects in an open-...See full text at original site
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引用元:
https://doi.org/10.1016/j.psychres.2021.114030

データ提供:米国国立医学図書館(NLM)

Switching Antipsychotics: A Potential Solution for Prolactin Elevation

Managing hyperprolactinemia, an increase in prolactin levels, in patients receiving antipsychotic medications is a constant challenge for psychiatrists. This study, a post hoc analysis, delves into the effects of switching from paliperidone palmitate to aripiprazole lauroxil in patients with schizophrenia. The researchers investigated the impact of this switch on prolactin levels and sexual side effects. Their findings demonstrate that switching from paliperidone palmitate to aripiprazole lauroxil significantly reduced prolactin levels and improved sexual side effects in patients with schizophrenia. This suggests a potential solution for managing the adverse effects of antipsychotic medications.

Aripiprazole Lauroxil: A Promising Option for Managing Hyperprolactinemia and Sexual Side Effects

The study provides valuable insights into the benefits of switching from paliperidone palmitate to aripiprazole lauroxil in patients with schizophrenia. The significant reduction in prolactin levels and the improvement in sexual side effects suggest that this switch could be a viable option for managing these common adverse effects associated with antipsychotic medications. The results underscore the importance of personalized treatment approaches and the ongoing search for effective strategies to minimize the side effects of medications.

Balancing Mental and Physical Well-Being

This study highlights the importance of managing the side effects of medications while addressing the underlying mental health condition. It's crucial to remember that mental and physical well-being are intertwined, and finding the right balance is essential for overall health. Open communication with your healthcare provider is vital to discuss potential side effects and explore treatment options that minimize their impact on your quality of life. As the sand dunes shift and change in the desert, so too can our understanding of mental health and the management of its associated conditions. This study serves as a reminder to continue seeking new ways to improve the lives of those affected by mental illness.

Dr.Camel's Conclusion

This study provides valuable insights into the potential benefits of switching from paliperidone palmitate to aripiprazole lauroxil in patients with schizophrenia. The observed reduction in prolactin levels and improvement in sexual side effects highlight the need for personalized treatment approaches and ongoing research to minimize the adverse effects of antipsychotic medications. This study underscores the complex interplay between mental and physical well-being and the importance of open communication with healthcare providers.

Date :
  1. Date Completed 2021-10-22
  2. Date Revised 2021-10-22
Further Info :

Pubmed ID

34118485

DOI: Digital Object Identifier

10.1016/j.psychres.2021.114030

Related Literature

SNS
PICO Info
in preparation
Languages

English

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