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Effectiveness of naloxegol in patients with cancer pain suffering from opioid-induced constipation.
Author: BranisteViorica, LemaireAntoine, NarcisoBérengère, PiloquetFrançois-Xavier, PointreauYoann, SabatéJean-Marc
Original Abstract of the Article :
Naloxegol, an oral once-daily peripherally acting mu-opioid receptor antagonist, is indicated for the treatment of opioid-induced constipation (OIC) with inadequate response to laxative(s), in cancer and non-cancer patients. This study mainly aimed to assess in real-life conditions the efficacy and ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549935/
データ提供:米国国立医学図書館(NLM)
Naloxegol for Opioid-Induced Constipation: A Relief in the Desert of Pain Management
Navigating the desert of pain management can be a challenging endeavor, particularly when dealing with opioid-induced constipation (OIC), a common side effect of opioid therapy. This study examines the effectiveness and safety of naloxegol, a peripherally acting mu-opioid receptor antagonist, in treating OIC in patients with cancer pain. The researchers aimed to assess the efficacy of naloxegol in real-world settings, evaluating its impact on patient quality of life.
Naloxegol: A Potential Oasis in the Desert
The study focused on cancer pain patients who had not responded adequately to laxatives. The findings indicate that naloxegol effectively addressed OIC, offering relief from this common and often debilitating side effect of opioid therapy.
Navigating the Sands of Opioid-Induced Constipation
This study provides valuable information for healthcare professionals and patients navigating the complexities of pain management. It highlights the potential of naloxegol as a safe and effective treatment for OIC, offering a glimmer of hope in the desert of managing this challenging side effect.
Dr.Camel's Conclusion
This study, like a oasis in the desert, offers a potential solution to the challenge of opioid-induced constipation in cancer pain patients. Naloxegol's effectiveness in this setting suggests a promising avenue for improving patient comfort and quality of life, making the journey through pain management a bit more manageable.
Date :
- Date Completed 2021-10-28
- Date Revised 2022-02-18
Further Info :
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English
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