[Colonic Mass Secondary to Sevelamer-associated Rectal Ulcer].

Author: ByeonJeong-Sik, HongSeung-Mo, HwangSung Wook, LeeJin Hee, MyungSeung-Jae, ParkJin Hwa, ParkSang Hyoung, ShinJin Ho, YangDong-Hoon, YangSuk-Kyun, YeByong Duk

Paper Details 
Original Abstract of the Article :
The phosphorous balance is clinically important in increasing the long-term outcomes and preventing complications of end-stage renal disease. Sevelamer is a phosphate binder used widely to regulate hyperphosphatemia. On the other hand, gastrointestinal side effects increase with increasing sevelamer...See full text at original site
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引用元:
https://doi.org/10.4166/kjg.2021.037

データ提供:米国国立医学図書館(NLM)

Sevelamer-Associated Rectal Ulcer: A Case Study

This research delves into the critical area of phosphate balance in end-stage renal disease. It explores the use of sevelamer, a commonly prescribed phosphate binder, and its potential side effects. The authors employed a case study approach to investigate a 29-year-old male with end-stage renal disease who developed a colonic mass. They used a combination of clinical observation, imaging techniques, and histopathological examination to pinpoint the cause. The study revealed the presence of sevelamer crystals in the rectal exudate, leading to the diagnosis of a sevelamer-associated rectal ulcer.

Sevelamer-Induced Complications: A Rare Occurrence

This case study underscores the potential for sevelamer to induce gastrointestinal complications, even though it is commonly used to manage hyperphosphatemia. The patient's symptoms, initially attributed to Clostridioides difficile-associated diarrhea, turned out to be related to sevelamer-induced rectal ulceration. This highlights the importance of considering rare side effects when interpreting clinical findings, especially in patients with complex medical histories.

The Importance of Diligent Monitoring

The study emphasizes the importance of careful monitoring for potential gastrointestinal side effects in patients taking sevelamer. Patients should be made aware of these possible complications and encouraged to report any unusual symptoms promptly. Healthcare providers should be vigilant in assessing patients on sevelamer, especially those with a history of gastrointestinal issues, to ensure timely diagnosis and management of potential complications.

Dr.Camel's Conclusion

This case study serves as a reminder that even common medications can have unexpected consequences. It highlights the importance of considering a broad range of potential causes when diagnosing a patient's condition. Like a camel navigating the vast desert, healthcare professionals must be alert to the subtle signs of potential complications, ensuring the wellbeing of their patients.
Date :
  1. Date Completed 2021-11-12
  2. Date Revised 2021-11-12
Further Info :

Pubmed ID

34158451

DOI: Digital Object Identifier

10.4166/kjg.2021.037

Related Literature

SNS
PICO Info
in preparation
Languages

Korean

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