Paper Details 
Original Abstract of the Article :
<i>Background and Objectives</i>: Bromelain is a mixture of protease obtained from pineapple fruits or stems. Even though the biological mechanism of action of bromelain has not been completely understood, it is well known that bromelain possesses anticancer, anti-inflammatory and immunomodulatory ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227231/

データ提供:米国国立医学図書館(NLM)

Bromelain: A Potential Oasis in the Desert of Dental Pulp Inflammation

In the complex landscape of oral health, inflammation of the dental pulp is a common challenge. This study explores the potential of bromelain, a protease derived from pineapples, to combat this inflammation. The researchers investigated the anti-inflammatory effects of bromelain on lipopolysaccharide (LPS)-induced inflammation in human dental pulp cells (hDPCs) using a variety of laboratory techniques, including Western blotting, immunofluorescence staining, and enzyme-linked immunosorbent assay. They found that bromelain significantly reduced the expression of inflammatory cytokines, including interleukin-1β, interleukin-6, and interleukin-8, in hDPCs. Furthermore, bromelain inhibited the activation of key signaling pathways, such as NF-κB and MAPK, which are crucial for inflammatory responses. These findings suggest that bromelain might have the potential to be used for regenerative endodontics, including vital pulp therapy.

Bromelain: A Powerful Anti-Inflammatory Agent

This study offers a glimmer of hope in the desert of dental inflammation, demonstrating bromelain's potential to effectively reduce inflammation in dental pulp cells. The study's findings indicate that bromelain not only suppresses the production of inflammatory cytokines but also regulates the signaling pathways that drive inflammation. This remarkable ability could lead to novel treatments for dental pulp inflammation, potentially reducing the need for invasive procedures.

Harnessing the Power of Pineapple: A Natural Approach to Dental Health

The study suggests that bromelain, a naturally occurring enzyme found in pineapples, could hold the key to combating dental pulp inflammation. This finding opens the door to exploring natural, less invasive approaches to dental health. While further research is needed to confirm the effectiveness and safety of bromelain for treating dental pulp inflammation, this study provides a promising starting point for exploring new avenues for oral health care.

Dr.Camel's Conclusion

This study is a testament to the power of nature, demonstrating the potential of bromelain to quench the flames of dental pulp inflammation. It offers a promising glimpse into the future of oral health care, potentially revolutionizing the way we treat dental problems.

Date :
  1. Date Completed 2021-07-05
  2. Date Revised 2021-07-05
Further Info :

Pubmed ID

34201357

DOI: Digital Object Identifier

PMC8227231

Related Literature

SNS
PICO Info
in preparation
Languages

English

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