Effects of nintedanib by inclusion criteria for progression of interstitial lung disease.

Author: , BehrJuergen, BelloliElizabeth A, BrownKevin K, DevarajAnand, FlahertyKevin R, GoeldnerRainer-Georg, KreuterMichael, LancasterLisa H, MaherToby M, PadillaMaria, Schlenker-HercegRozsa, TetzlaffKay, WalshSimon L F

Paper Details 
Original Abstract of the Article :
BACKGROUND: The INBUILD trial investigated nintedanib METHODS: Subjects had a fibrosing ILD other than idiopathic pulmonary fibrosis and met the following criteria for ILD progression within the 24 months before screening despite management deemed appropriate in clinical practice: Group A, relativ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812469/

データ提供:米国国立医学図書館(NLM)

Nintedanib for Interstitial Lung Disease: A Targeted Approach to Managing Lung Fibrosis

The fight against [interstitial lung disease (ILD)] is a constant battle, and this study investigates the role of [nintedanib] in managing ILD progression. The authors conducted a comprehensive analysis of data from the INBUILD trial, examining the efficacy of nintedanib in different subgroups of patients with progressive fibrosing ILDs, defined by specific criteria related to lung function decline and radiological changes.

Precision in Treatment: Tailoring Nintedanib Therapy for Individual Patients

This study demonstrates the importance of personalized approaches to managing ILD progression. The authors reveal that nintedanib may have differential effects depending on the specific criteria used to define ILD progression. The findings suggest that nintedanib may be most effective in patients with a more significant decline in lung function, highlighting the need for a tailored approach to treatment based on individual patient characteristics.

The Future of ILD Management: A Collaborative Effort

This study underscores the importance of ongoing research and collaboration in the field of ILD. The authors emphasize the need for further investigation into the optimal use of nintedanib in different ILD subgroups, as well as the development of new therapeutic strategies for this challenging disease. This research highlights the need for a multidisciplinary approach to ILD management, involving healthcare professionals, researchers, and patients to improve outcomes and advance our understanding of this complex condition.

Dr. Camel's Conclusion

This study provides valuable insights into the nuances of nintedanib therapy for ILD progression, highlighting the importance of personalized approaches to treatment. The research emphasizes the need for ongoing investigation and collaboration to refine our understanding of this complex disease and develop effective therapeutic strategies for individual patients.

Date :
  1. Date Completed 2022-04-06
  2. Date Revised 2022-04-06
Further Info :

Pubmed ID

34210788

DOI: Digital Object Identifier

PMC8812469

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Languages

English

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