Preseptal cellulitis, intraocular inflammatory reaction and corneal persistent epithelial defect as side effects of avapritinib.

Author: Díaz ValleDavid, García CarideSara, MarquinaGloria

Paper Details 
Original Abstract of the Article :
Avapritinib is a tyrosine kinase inhibitor currently being investigated on clinical trials for the treatment of unresectable or metastatic gastrointestinal stromal tumour (GIST). It has been recently approved by the Food and Drug Administration and the European Medicines Agency for the treatment of ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/34282744

データ提供:米国国立医学図書館(NLM)

Exploring the Ocular Side Effects of Avapritinib

The development of

targeted therapies

for cancer has revolutionized treatment approaches, offering new hope for patients. However, it is crucial to understand the potential side effects of these therapies to optimize patient care. This case report highlights the occurrence of preseptal cellulitis, intraocular inflammatory reaction, and corneal persistent epithelial defect in a patient treated with avapritinib, a tyrosine kinase inhibitor used for the treatment of gastrointestinal stromal tumors (GIST). The report underscores the importance of vigilance in monitoring potential ocular side effects associated with avapritinib.

A Case of Avapritinib-Related Ocular Side Effects

The report details the case of a 76-year-old woman diagnosed with stage IV GIST who developed a series of ocular complications following treatment with avapritinib. This case report is like discovering a hidden oasis in the desert, offering a glimpse into the potential side effects of a new therapy. The patient's experience serves as a valuable reminder for healthcare professionals to carefully monitor patients receiving avapritinib, particularly for the development of ocular side effects.

Implications for Clinical Practice

The case report emphasizes the need for further research to investigate the potential ocular toxicity associated with avapritinib. The findings suggest that careful ophthalmologic monitoring might be necessary for patients receiving avapritinib, especially those with pre-existing eye conditions. This research underscores the importance of vigilance and careful observation in clinical practice to ensure patient safety.

Dr.Camel's Conclusion

This case report raises awareness of potential ocular side effects associated with avapritinib, a tyrosine kinase inhibitor used for the treatment of gastrointestinal stromal tumors. The report highlights the importance of vigilance in monitoring patients receiving avapritinib, particularly for the development of ocular complications. This research is like a desert explorer uncovering a new path, reminding us to stay alert and adapt to the changing landscape of drug-related side effects.

Date :
  1. Date Completed 2022-02-03
  2. Date Revised 2022-02-03
Further Info :

Pubmed ID

34282744

DOI: Digital Object Identifier

00001813-202112000-00020

SNS
PICO Info
in preparation
Languages

English

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