Loxapine in patient with clozapine-resistant psychosis.

Author: AuduAlexandra, ErleyJennifer, GoldsboroughSarah, VandenBergAmy

Paper Details 
Original Abstract of the Article :
Clozapine is recognized as the drug of choice for treatment-refractory schizophrenia, but use may be limited because of strict monitoring requirements and adverse effects including severe neutropenia, seizures, and myocarditis. Loxapine is a first-generation antipsychotic with similarities to clozap...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287867/

データ提供:米国国立医学図書館(NLM)

Loxapine: A Potential Alternative for Clozapine-Resistant Psychosis

Clozapine is a widely recognized treatment for treatment-refractory schizophrenia, but its use is often limited by strict monitoring requirements and potential adverse effects. This case report describes a patient with severe paranoid schizophrenia who did not respond to clozapine but experienced improvement after switching to loxapine, a first-generation antipsychotic with structural similarities to clozapine. The authors present a case study highlighting the potential role of loxapine as an alternative treatment option.

A New Path: Exploring Treatment Options for Psychosis

This case report suggests that loxapine may be a viable treatment option for patients with treatment-refractory schizophrenia who do not tolerate or respond to clozapine. The research emphasizes the importance of exploring alternative therapies for patients with complex and challenging psychiatric conditions.

Finding Solutions: Managing Treatment-Resistant Psychosis

This study provides a valuable case study for clinicians treating patients with treatment-resistant psychosis. The research highlights the potential benefits of considering loxapine as an alternative therapeutic option, offering hope for individuals struggling with these challenging conditions.

Dr. Camel's Conclusion

The search for effective treatments for psychosis can be like a camel searching for a hidden oasis in a vast and unforgiving desert. This case report provides a glimmer of hope, suggesting that loxapine may be a valuable alternative for patients who have not responded to other treatments. While further research is needed, this case offers a potential path toward better management of this complex condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-07-29
Further Info :

Pubmed ID

34316424

DOI: Digital Object Identifier

PMC8287867

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Languages

English

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