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Observational study on the response of tenofovir monotherapy versus tenofovir plus telbivudine dual therapy in patients with hepatitis B virus related acute on chronic liver failure.
Author: AkbarMohammad Fazle, DasDulal C, KhanSakirul, MahtabMamun A, MalakarDebraj, MamunAyub A, ManikAbul H, Noor-E-AlamSheikh M, RahmanSalimur, RahmanZakiur
Original Abstract of the Article :
INTRODUCTION: HBV is major health problem globally due to complications, including ACLF, cirrhosis and hepa¬tocellular carcinoma. ACLF due to exacerbation of CHB is associate with 30%-70% mortality. Reduction of HBV-DNA is therefore a target of therapy in ACLF-B. METHODS: Patients with spontaneous ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284233/
データ提供：米国国立医学図書館（NLM）
Tenofovir Monotherapy vs. Dual Therapy for HBV-Related ACLF
This study explores the efficacy and safety of [tenofovir monotherapy] compared to [tenofovir plus telbivudine dual therapy] in patients with [hepatitis B virus (HBV)-related acute on chronic liver failure (ACLF)]. The researchers investigated the impact of these treatment strategies on [HBV-DNA reduction, ascites resolution, liver-related complications, therapy-related adverse effects, and survival] in patients with ACLF-B. This research delves into the potential advantages and disadvantages of different treatment approaches for HBV-related ACLF.
A Comparative Look at Treatment Strategies for HBV-Related ACLF
This study provides valuable insights into the treatment of HBV-related ACLF, suggesting that the combination of telbivudine and tenofovir may be a safer and more effective approach compared to tenofovir monotherapy. The study highlights the importance of individualized treatment decisions, considering factors such as [nephrotoxicity, HBV-DNA levels, and overall health status].
Navigating the Oasis of Liver Health: A Holistic Approach
This study underscores the importance of personalized treatment plans for HBV-related ACLF. The desert of liver health is a complex and challenging landscape, but with the right guidance and support, we can find ways to maintain optimal liver function and well-being. It's essential to work closely with your healthcare provider to develop a comprehensive treatment plan that addresses your individual needs.
Dr.Camel's Conclusion
This study, "Observational study on the response of tenofovir monotherapy versus tenofovir plus telbivudine dual therapy in patients with hepatitis B virus related acute on chronic liver failure," compared the efficacy and safety of tenofovir monotherapy and tenofovir plus telbivudine dual therapy in patients with HBV-related ACLF. The study suggests that dual therapy may be a safer and more effective approach, highlighting the importance of individualized treatment decisions for this complex condition.
Date :
- Date Completed n.d.
- Date Revised 2023-09-20
Further Info :
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