Effectiveness of topical glyceryl trinitrate in treatment of tendinopathy - systematic review and meta-analysis.

Author: JohanssonJouni, JuholaJuhani, KemppiViljami, SaltychevMikhail

Paper Details 
Original Abstract of the Article :
PURPOSE: The objective of this meta-analysis was to evaluate the evidence on the effectiveness of glycerin trinitrate (NTG) measured by pain severity. MATERIALS AND METHODS: CENTRAL, MEDLINE, EMBASE, SCOPUS, and WEB of SCIENCE databases were searched in November 2020. The study selection was perfor...See full text at original site
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引用元:
https://doi.org/10.1080/09638288.2021.1958067

データ提供:米国国立医学図書館(NLM)

Topical Glyceryl Trinitrate for Tendinopathy: A Journey Through the Scientific Desert

The field of [tendinopathy] is vast and complex, with researchers continuously seeking new and effective treatment options. This meta-analysis investigates the effectiveness of [topical glyceryl trinitrate (NTG)] in reducing pain associated with tendinopathy. The researchers conducted a comprehensive review of 87 studies, ultimately focusing on 8 randomized controlled trials (RCTs) to evaluate the impact of NTG on pain severity. The results of this meta-analysis are quite intriguing, as they suggest that NTG may not be significantly more effective than placebo in reducing pain. While some studies showed borderline significance, the overall findings indicate that NTG may not offer a substantial benefit for individuals with tendinopathy.

Navigating the Desert of Tendinopathy: A Search for Effective Pain Relief

The meta-analysis's findings suggest that topical NTG may not be a reliable solution for reducing pain in tendinopathy. While other treatment options may be more effective, the study's results provide valuable insights into the potential limitations of NTG in this context.

Finding the Right Oasis: Exploring Other Treatment Options

Imagine a world where individuals with tendinopathy can find effective and safe pain relief. This research, while not conclusive in favor of topical NTG, underscores the need for continued research and exploration of alternative treatment approaches to manage this condition.

Dr. Camel's Conclusion

Just as a camel may encounter dry and barren stretches in its journey across the desert, individuals with tendinopathy may find limited relief from topical NTG. This meta-analysis highlights the need for continued exploration of alternative treatment options, ensuring that those with tendinopathy can find the right oasis of pain relief.

Date :
  1. Date Completed 2022-10-12
  2. Date Revised 2022-12-20
Further Info :

Pubmed ID

34330192

DOI: Digital Object Identifier

10.1080/09638288.2021.1958067

Related Literature

SNS
PICO Info
in preparation
Languages

English

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