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A review of a diazepam nasal spray for the treatment of acute seizure clusters and prolonged seizures.

Author: HigdonLindsay M, SperlingMichael R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Acute repetitive seizures (ARS) in epilepsy patients can negatively impact quality of life, daily function, and increase healthcare utilization. Intranasal benzodiazepines are a promising at-home rescue medication option as they are socially acceptable and easier to administer than rectal drugs.
Paper Details　
Original Abstract of the Article :
Some people with epilepsy experience acute repetitive seizures (ARS), also termed seizure clusters, which have a negative impact on patient and caregiver quality of life, emotional wellbeing, daily function, and may pose risk of injury or death. In addition, these events increase healthcare utilizat...See full text at original site
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引用元：
https://doi.org/10.1080/14737175.2021.1965880

データ提供：米国国立医学図書館（NLM）

Diazepam Nasal Spray: A Promising Rescue Medication for Seizures

This review examines the potential of a diazepam nasal spray for treating acute seizure clusters and prolonged seizures in individuals with epilepsy. Seizure clusters, also known as acute repetitive seizures (ARS), can significantly impact patients’ quality of life, leading to increased risk of injury and emergency department visits. The authors explore the advantages of intranasal diazepam as a readily available rescue medication, offering a convenient and socially acceptable alternative to traditional methods of administering benzodiazepines.

A Convenient and Effective Rescue Medication

The review highlights the potential benefits of diazepam nasal spray as a readily available rescue medication for individuals with epilepsy. The intranasal formulation offers a convenient and socially acceptable alternative to traditional methods of administering benzodiazepines, making it more readily available to patients experiencing seizure clusters. The review suggests that diazepam nasal spray could play a significant role in reducing the burden of seizures and improving the quality of life for individuals with epilepsy.

Improving Seizure Management and Quality of Life

This review provides valuable insights into the evolving landscape of seizure management. The potential of diazepam nasal spray as a rescue medication offers a promising approach to improving the quality of life for individuals with epilepsy. The review underscores the importance of exploring innovative and convenient methods for delivering medications, particularly in the context of managing acute and unpredictable medical events.

Dr.Camel's Conclusion

Seizures can be unpredictable and disruptive, much like a sudden sandstorm that can disrupt a camel’s journey. This review highlights the potential of diazepam nasal spray to provide a much-needed lifeline for individuals with epilepsy, offering a convenient and effective way to manage seizures and improve their overall well-being. It’s a reminder that innovation and a focus on patient needs are essential for advancing healthcare outcomes.
Date :
  1. Date Completed 2022-01-31
  2. Date Revised 2022-01-31
Further Info :

Pubmed ID

34374629

DOI: Digital Object Identifier

10.1080/14737175.2021.1965880

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・Effects of diazepam nasal spray
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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