Development of biodegradable thin films for efficient, specific and controlled delivery of capecitabine.

Author: AjmalMuhammad, BhattiMoazzam Hussain, ChaudhryGul-E-Saba, GulIrum, YunusUzma

Paper Details 
Original Abstract of the Article :
Cancer is the leading cause of death worldwide. Capecitabine (CP) shows severe side effects because of early metabolism in stomach that affects the normal cells and organs, particularly liver and stomach. In this scope, we report the biocompatible, nontoxic polymeric thin films loaded with anti-canc...See full text at original site
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引用元:
https://doi.org/10.1088/1748-605X/ac1c61

データ提供:米国国立医学図書館(NLM)

Targeted Drug Delivery: A Camel's Quest for Precise Treatment

Cancer treatment often involves systemic administration of chemotherapy drugs, which can lead to severe side effects due to the drug's impact on healthy cells and organs. This research explores the potential of biodegradable thin films for targeted and controlled delivery of capecitabine, a chemotherapy drug used to treat breast cancer. The study developed thin films made from chitosan and polyvinyl alcohol, loaded with capecitabine, and evaluated their ability to deliver the drug effectively and specifically to the target site. The study found that the thin films were biocompatible, nontoxic, and capable of controlled release of capecitabine, significantly enhancing the drug's efficacy against breast cancer cells while minimizing side effects.

Thin Film Technology: A Desert Oasis for Targeted Drug Delivery

The study's findings demonstrate the potential of thin film technology for targeted and controlled drug delivery, offering a promising approach to improving cancer treatment. This technology has the potential to enhance drug efficacy, reduce side effects, and improve patient outcomes. Further research is needed to optimize the use of these thin films and explore their potential in other cancer types.

Navigating the Desert of Cancer Treatment: A Patient's Perspective

Cancer treatment can be a challenging and often grueling journey, with many patients experiencing debilitating side effects. This research offers a ray of hope by demonstrating the potential of targeted drug delivery to improve treatment outcomes and minimize side effects. By developing more precise and effective methods for delivering chemotherapy drugs, we can help patients navigate the desert of cancer treatment with greater comfort and hope.

Dr.Camel's Conclusion

This study is a reminder that the desert of cancer treatment is constantly evolving, with new technologies and approaches emerging that hold the potential to transform patient care. By embracing innovation and pursuing new avenues for targeted drug delivery, we can continue to explore the desert of cancer treatment, seeking new oases of hope and healing for those battling this devastating disease.

Date :
  1. Date Completed 2022-02-25
  2. Date Revised 2023-07-21
Further Info :

Pubmed ID

34375958

DOI: Digital Object Identifier

10.1088/1748-605X/ac1c61

Related Literature

SNS
PICO Info
in preparation
Languages

English

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