Lactobacillus fermentum PS150 promotes non-rapid eye movement sleep in the first night effect of mice.

Author: ChenChieh-Wen, ChengYu-Ting, ChuHsu-Feng, LinAlexander, ShihChing-Ting, TsaiYing-Chieh, WuChien-Chen, YangCheryl C H

Paper Details 
Original Abstract of the Article :
The first night effect (FNE) is a type of sleep disturbance caused by an unfamiliar environment, which leads to difficulty falling asleep and reduced sleep duration. Previously, we reported that Lactobacillus fermentum PS150 (PS150) improves sleep conditions in a pentobarbital-induced sleep mouse mo...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357945/

データ提供:米国国立医学図書館(NLM)

Lactobacillus fermentum PS150 Promotes Non-Rapid Eye Movement Sleep in the First Night Effect of Mice

This study investigated the effects of Lactobacillus fermentum PS150 (PS150), a probiotic strain, on sleep disturbance caused by the first night effect (FNE) in mice. The FNE is a type of sleep disruption that occurs in unfamiliar environments, leading to difficulty falling asleep and reduced sleep duration. The study found that PS150 administration improved non-rapid eye movement (NREM) sleep length in mice experiencing the FNE. Moreover, PS150 effectively reduced sleep latency and time spent restoring normal levels of REM sleep, suggesting potential benefits for improving sleep quality in unfamiliar environments.

Probiotic Potential for Sleep Enhancement: Exploring the Link Between Gut Health and Sleep

The study provides evidence for the potential of PS150, a probiotic strain, to improve sleep quality in mice experiencing the FNE. The findings suggest that PS150 may promote NREM sleep, reduce sleep latency, and facilitate a quicker return to normal REM sleep patterns. This research opens doors for exploring the intricate connection between gut health and sleep quality, potentially leading to novel approaches for improving sleep in various contexts.

Navigating the Sands of Sleep: Exploring the Gut-Brain Connection

This research highlights the intriguing relationship between gut health and sleep, suggesting that probiotic interventions may offer a promising avenue for addressing sleep disturbances. The study’s findings encourage further exploration of the gut-brain axis and its role in regulating sleep. As a wise old camel, I’ve learned that the journey to better sleep often involves understanding the interconnectedness of our internal systems and exploring novel ways to promote harmony and balance.

Dr.Camel's Conclusion

This study unveils the potential of PS150, a probiotic strain, to improve sleep quality in mice experiencing the FNE. The findings suggest that PS150 may offer a novel and promising approach to addressing sleep disturbances in unfamiliar environments. Remember, exploring the intricate interplay between gut health and sleep is like navigating a vast desert, requiring a keen understanding of the connections between our internal systems and the potential of probiotics for promoting overall well-being.
Date :
  1. Date Completed 2021-11-12
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

34381098

DOI: Digital Object Identifier

PMC8357945

Related Literature

SNS
PICO Info
in preparation
Languages

English

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