Paper Details 
Original Abstract of the Article :
OBJECTIVE: Common side effects of clozapine may affect the treatment process negatively. In this study, we aimed to assess the common side effects and the prevalence of metabolic syndrome in schizophrenia patients treated with clozapine, and to study their relationship with clinical variables and di...See full text at original site
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引用元:
https://doi.org/10.5080/u25737

データ提供:米国国立医学図書館(NLM)

Common Side Effects and Metabolic Syndrome Due to Clozapine

Clozapine, an antipsychotic medication used to treat schizophrenia, is known for its efficacy in managing severe symptoms. However, it can also lead to various side effects, including metabolic disturbances. This study investigates the prevalence of common side effects and metabolic syndrome in patients taking clozapine, exploring their association with clinical variables and disability. Researchers, like intrepid explorers traversing the desert of mental health treatment, are seeking to optimize the use of clozapine while minimizing potential adverse effects.

The study found that common side effects associated with clozapine included hypersalivation, fatigue, sedation, and constipation. The prevalence of metabolic syndrome was high, affecting 50% of the patients in the study. The researchers also observed a significant association between constipation and clozapine dose, and dizziness and norclozapine plasma levels. The study also highlighted the relationship between disability and the severity of psychopathology, the number of side effects, and age at onset of illness.

Navigating the Desert of Mental Health Treatment

This research underscores the importance of carefully monitoring patients taking clozapine for potential side effects and metabolic disturbances. The study's findings emphasize the need for proactive measures to manage these issues, potentially improving treatment outcomes and minimizing disability.

A Balanced Approach to Clozapine Treatment

The desert of mental health treatment is often characterized by a delicate balance between efficacy and safety. This study provides valuable insights into the potential risks and benefits of clozapine, highlighting the need for a personalized and individualized approach to treatment.

Dr.Camel's Conclusion

This study highlights the complexities of managing clozapine treatment, emphasizing the importance of careful monitoring for side effects and metabolic disturbances. The research underscores the need for a collaborative approach between patients and healthcare providers to optimize treatment outcomes while minimizing potential adverse events.

Date :
  1. Date Completed 2021-10-28
  2. Date Revised 2022-03-28
Further Info :

Pubmed ID

34392505

DOI: Digital Object Identifier

10.5080/u25737

Related Literature

SNS
PICO Info
in preparation
Languages

English

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