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Effects of garden cress, fenugreek and black seed on the pharmacodynamics of metoprolol: an herb-drug interaction study in rats with hypertension.
Author: AhadAbdul, Al-JenoobiFahad I, Al-MohizeaAbdullah M, AlamMohd Aftab, Bin JardanYousef A, RaishMohammad
Original Abstract of the Article :
CONTEXT: Garden cress (GC), fenugreek (FG), and black seed (BS) are traditional herbal medicine for managing hypertension. OBJECTIVE: The effects of the three herbs on the pharmacodynamics of metoprolol tartrate (MT) in hypertensive rats were investigated. MATERIALS AND METHODS: Wistar rats were d...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366631/
データ提供:米国国立医学図書館(NLM)
Herbal Remedies for Hypertension: Exploring Potential Interactions
Hypertension, a major health concern worldwide, can lead to serious cardiovascular complications. This study examines the potential interactions between three traditional herbal remedies – garden cress, fenugreek, and black seed – and the antihypertensive medication metoprolol tartrate.
The researchers investigated the effects of these herbs on blood pressure in hypertensive rats. They found that all three herbs had a blood pressure-lowering effect on their own and when combined with metoprolol tartrate. However, they cautioned that the concurrent use of these herbs with drugs, especially those metabolized by the CYP450 2D6 enzyme, could potentially lead to drug interactions.
The Importance of Understanding Herb-Drug Interactions
This study highlights the importance of understanding potential herb-drug interactions, especially for individuals who use both herbal remedies and conventional medications. It emphasizes the need for caution and close monitoring when using herbal remedies alongside prescribed drugs to avoid potential adverse effects.
Navigating the Desert of Herbal Remedies
This study is like a camel caravan navigating the vast and sometimes treacherous desert of herbal remedies. It warns travelers to be aware of potential hidden dangers, like herb-drug interactions, and to be cautious when exploring uncharted territory.
Dr. Camel's Conclusion
This study is like a camel caravan navigating the complex landscape of herbal remedies. While these remedies may offer potential benefits, it is crucial to be aware of potential interactions with conventional medications and to seek guidance from a qualified healthcare professional before incorporating them into your treatment plan.
Date :
- Date Completed 2022-01-06
- Date Revised 2022-04-25
Further Info :
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