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Indirect treatment comparison of solriamfetol, modafinil, and armodafinil for excessive daytime sleepiness in obstructive sleep apnea.

Author: BronMorgan, BujanoverShay, KratochvilDavid, LucasEleanor, MennoDiane, PatelDipen, RonnebaumSarah, StepnowskyCarl

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This meta-analysis compared the efficacy and safety of medications for treating excessive daytime sleepiness associated with obstructive sleep apnea. Solriamfetol, modafinil, and armodafinil were evaluated.
Paper Details　
Original Abstract of the Article :
Excessive daytime sleepiness associated with obstructive sleep apnea affects 9%-22% of continuous positive airway pressure-treated patients. An indirect treatment comparison meta-analysis was performed to compare efficacy and safety of medications (solriamfetol, modafinil, and armodafinil) approved ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726370/

データ提供：米国国立医学図書館（NLM）

Comparative Efficacy and Safety of Medications for Excessive Daytime Sleepiness

This indirect treatment comparison meta-analysis evaluates the efficacy and safety of medications approved to treat excessive daytime sleepiness (EDS) associated with obstructive sleep apnea (OSA). The study compares solriamfetol, modafinil, and armodafinil, examining their effectiveness and safety profiles. The analysis provides valuable information for clinicians seeking to optimize treatment for EDS in patients with OSA.

Optimizing Treatment for EDS in OSA: A Comparative Analysis

The study's findings provide a comprehensive comparison of the efficacy and safety of different medications for EDS in OSA. Clinicians can utilize this information to select the most appropriate treatment based on individual patient characteristics and preferences.

Managing EDS in OSA: Seeking Expert Advice

If you are experiencing EDS related to OSA, consulting with a sleep specialist is essential. They can diagnose the underlying cause, recommend appropriate treatment strategies, and guide you through managing your condition.

Dr.Camel's Conclusion

This research, like a camel navigating the vast desert of sleep disorders, provides a valuable comparison of medications used to treat excessive daytime sleepiness (EDS) in obstructive sleep apnea (OSA). The study offers insights into the efficacy and safety profiles of different medications, empowering clinicians to make informed decisions about treatment and support the well-being of their patients.

Date :
  1. Date Completed 2021-12-23
  2. Date Revised 2022-12-02
Further Info :

Pubmed ID

34402784

DOI: Digital Object Identifier

PMC8726370

Related Literature

Article Analysis
・Effects of armodafinil・Effects of solriamfetol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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