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Maoto, a traditional Japanese medicine, controls acute systemic inflammation induced by polyI:C administration through noradrenergic function.

Author: KadotaAyumi, KannoHitomi, NakayamaAkiko, NishiAkinori, OguraKeisuke, TaharaYoshio

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the anti-inflammatory effects of maoto, a traditional Japanese medicine, in a mouse model of acute inflammation. Maoto significantly reduced TNF-α levels and increased IL-10 production, independent of IL-10 and T cells. The study suggests that maoto mediates its anti-inflammatory effects via β-adrenergic receptors in vivo.
Paper Details　
Original Abstract of the Article :
Maoto, a traditional Japanese medicine (Kampo), is widely used to treat upper respiratory tract infections, including influenza virus infection. Although maoto is known to inhibit pro-inflammatory responses in a rodent model of acute inflammation, its underlying mechanism remains to be determined. I...See full text at original site
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引用元：
https://doi.org/10.1016/j.gene.2021.145921

データ提供：米国国立医学図書館（NLM）

Maoto: A Traditional Japanese Medicine with Anti-Inflammatory Properties

The realm of traditional medicine is a vast and ancient desert, filled with time-tested remedies that have been passed down through generations. This study investigates the anti-inflammatory properties of maoto, a traditional Japanese medicine, in a mouse model of acute inflammation. The researchers examined the mechanisms by which maoto exerts its anti-inflammatory effects, focusing on the role of noradrenergic function. Their findings provide valuable insights into the potential therapeutic applications of this traditional medicine.

Maoto's Anti-Inflammatory Mechanism: A Journey of Discovery

This study reveals the intriguing anti-inflammatory mechanism of maoto, demonstrating its ability to modulate immune responses and enhance noradrenergic function. The researchers observed that maoto effectively reduced pro-inflammatory cytokine production and increased anti-inflammatory cytokine levels. This research suggests that maoto could be a promising natural remedy for inflammatory conditions.

Harnessing the Power of Traditional Medicine: A New Frontier

The world of traditional medicine holds a wealth of knowledge and potential therapeutic benefits. This study provides a compelling case for further investigation of maoto and other traditional medicines to uncover their potential therapeutic applications. By combining traditional wisdom with modern scientific methods, we can unlock the treasures hidden within the vast desert of traditional medicine.

Dr. Camel's Conclusion

This research sheds light on the anti-inflammatory properties of maoto, a traditional Japanese medicine. It's a reminder that the world of traditional medicine holds a rich trove of knowledge and potential therapeutic benefits, waiting to be explored. This study encourages us to embrace the wisdom of ancient traditions and to continue exploring their applications in modern healthcare.

Date :
  1. Date Completed 2021-09-21
  2. Date Revised 2021-09-21
Further Info :

Pubmed ID

34454033

DOI: Digital Object Identifier

10.1016/j.gene.2021.145921

SNS
PICO Info
in preparation
Languages

English

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