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Hypotension from afatinib in epidermal growth factor receptor-mutated non-small cell lung cancer: a case report and literature review.

Author: ChenRuhua, DingHui, FenYan, JiXiuHai, TangZhiwei, ZhouGuanghui

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case report describes a patient with non-small cell lung cancer who developed hypotension after starting afatinib treatment. This emphasizes the importance of being aware of hypotension as a potential side effect of afatinib in this patient population.
Paper Details　
Original Abstract of the Article :
Side effects of afatinib are a problem in patients with advanced non-small cell lung cancer (NSCLC). However, little is known about the occurrence of afatinib-induced hypotension. An 81-year-old man with NSCLC had an epidermal growth factor receptor-positive genotype with the p.L861Q mutation in exo...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670351/

データ提供：米国国立医学図書館（NLM）

Afatinib: A Powerful Weapon with Potential Side Effects

Afatinib is a valuable weapon in the fight against non-small cell lung cancer (NSCLC). But like a warrior carrying a heavy armor, it comes with potential side effects. This case report highlights the importance of being aware of a specific side effect of afatinib: hypotension, or low blood pressure. The report discusses a patient who experienced hypotension after starting afatinib therapy, emphasizing the need for careful monitoring and management.

Navigating the Terrain of Side Effects

This case report serves as a cautionary tale, reminding us that even the most effective treatments can have unforeseen consequences. Imagine a desert traveler encountering a hidden sandstorm. Just as the traveler must adapt to the changing conditions, clinicians must be prepared to address unexpected side effects of medications. The report highlights the importance of being aware of the potential for hypotension in patients receiving afatinib.

Staying Vigilant in Cancer Treatment

The study emphasizes the need for vigilant monitoring of patients receiving afatinib therapy. This includes taking a proactive approach to identifying potential side effects like hypotension. Just as a camel would carefully survey the desert for signs of danger, clinicians must remain vigilant in managing their patients' health.

Dr.Camel's Conclusion

Afatinib is a powerful tool in the fight against NSCLC, but it is important to be aware of its potential side effects. This case report serves as a reminder that careful monitoring and management are crucial for maximizing the benefits of cancer treatment while minimizing the risks.

Date :
  1. Date Completed 2022-03-04
  2. Date Revised 2023-09-02
Further Info :

Pubmed ID

34486535

DOI: Digital Object Identifier

PMC8670351

Related Literature

Article Analysis
・Side Effects of afatinib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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