Future perspectives in diabesity treatment: Semaglutide, a glucagon-like peptide 1 receptor agonist (Review).

Author: NiculasCristina, TileaIoan, TilincaMariana Cornelia, TiucaRobert Aurelian, VargaAndreea

Paper Details 
Original Abstract of the Article :
Given their endemic prevalence in the past decades, obesity and type 2 diabetes mellitus (T2DM) have become a major sanitary burden with an important economic impact. Novel treatment options have been designed with the aim of reducing the numerous complications associated with these metabolic disord...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394024/

データ提供:米国国立医学図書館(NLM)

Semaglutide: A New Hope in the Fight Against Diabesity

This research explores the exciting potential of semaglutide, a glucagon-like peptide 1 receptor agonist (GLP-1 RA), in the context of [Diabesity]. Diabesity, a term highlighting the intertwined nature of obesity and type 2 diabetes mellitus (T2DM), is a growing concern worldwide. These conditions represent a major health burden, leading to numerous complications, increased morbidity and mortality, and a diminished quality of life.

Semaglutide, a long-acting GLP-1 RA, offers a promising new therapeutic approach to combat diabesity. Its unique mechanism of action targets multiple aspects of glucose metabolism, including glucose-dependent insulin secretion, glucagon inhibition, and delayed gastric emptying. Furthermore, semaglutide's effects on the central nervous system contribute to weight loss.

This review delves into the latest research on semaglutide, highlighting its efficacy in reducing blood glucose levels and promoting weight loss in both diabetic and non-diabetic individuals. It also discusses its potential cardiovascular benefits and explores potential side effects.

Semaglutide: A Multifaceted Weapon Against Diabesity

The research suggests that semaglutide holds significant potential for improving the management of diabesity. It offers a multifaceted approach to managing blood glucose levels, promoting weight loss, and potentially mitigating cardiovascular risk. This drug could become a game-changer in the fight against these chronic conditions, offering a more effective and comprehensive approach to treatment.

A Promising Horizon for Diabesity Management: The Role of Semaglutide

Semaglutide, with its unique properties and demonstrated efficacy, could usher in a new era of treatment for diabesity. It offers a targeted and effective approach to managing both obesity and type 2 diabetes, potentially improving the health and quality of life for millions of people around the world.

Dr. Camel's Conclusion

Semaglutide represents a significant advancement in the treatment of diabesity. Its ability to target multiple aspects of glucose metabolism, promote weight loss, and potentially reduce cardiovascular risk offers a promising solution for managing this complex health challenge.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-09-11
Further Info :

Pubmed ID

34504612

DOI: Digital Object Identifier

PMC8394024

Related Literature

SNS
PICO Info
in preparation
Languages

English

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