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Late-onset hypophysitis after discontinuation of nivolumab treatment for advanced skin melanoma: a case report.
Author: AntoniouSofia, BazazoGeorgios, BergChristian, PapadakisMarios, RöcklLudwig
Original Abstract of the Article :
Nivolumab is an anti-programmed cell death protein 1 antibody, typically used as cancer immunotherapy agent. Despite multiple clinical benefits it might cause autoimmune-related side-effects, often involving the endocrine system. To our knowledge, this is the first case of nivolumab-induced hypophys...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454065/
データ提供:米国国立医学図書館(NLM)
A Case of Late-Onset Hypophysitis: A Rare Side Effect of Nivolumab
Nivolumab, an immunotherapy drug used in cancer treatment, has revolutionized oncology. However, like a desert oasis that can also hide unexpected dangers, nivolumab can sometimes trigger autoimmune-related side effects. This case report describes a rare instance of late-onset hypophysitis, a condition affecting the pituitary gland, occurring several months after discontinuation of nivolumab treatment for advanced skin melanoma.
Navigating the Unknown: A Rare Side Effect
This case report highlights the importance of monitoring for potential side effects, even after discontinuation of immunotherapy drugs. It's like exploring a desert landscape - sometimes hidden dangers lurk beneath the surface. This case underscores the need for vigilance and careful follow-up care for patients receiving immunotherapy, ensuring early detection and management of potential complications.
A Reminder of Vigilance: The Importance of Monitoring
This report serves as a reminder that even innovative and life-saving treatments can have unexpected consequences. It's a reminder that the desert of medical knowledge is vast and full of surprises. This case emphasizes the importance of ongoing research to understand the full spectrum of side effects associated with immunotherapy drugs, ensuring the safety and well-being of patients.
Dr. Camel's Conclusion
While immunotherapy offers a beacon of hope for cancer patients, it's crucial to be aware of the potential for rare but serious side effects. This case report underscores the importance of careful monitoring and vigilant follow-up care for patients receiving immunotherapy, ensuring that they receive the best possible care and management of potential complications.
Date :
- Date Completed 2022-01-24
- Date Revised 2023-12-13
Further Info :
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English
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