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Neurosteroid-based intervention using Ganaxolone and Emapunil for improving stress-induced myelination deficits and neurobehavioural disorders.
Author: CrombieGabrielle K, HirstJonathan J, HodgsonDeborah M, PalliserHannah K, ShawJulia C, WalkerDavid W
Original Abstract of the Article :
Prenatal stress is associated with long-term disturbances in white matter development and behaviour in children, such as attention deficit hyperactivity disorder (ADHD) and anxiety. Oligodendrocyte maturation and myelin formation is a tightly orchestrated process beginning during gestation, and ther...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://doi.org/10.1016/j.psyneuen.2021.105423
データ提供:米国国立医学図書館(NLM)
Prenatal Stress and Myelination: A Desert of Brain Development Challenges
The field of [neurodevelopment] is increasingly exploring the long-term effects of [prenatal stress] on brain development and behavior. This study delves into the impact of [prenatal stress] on [myelination], a crucial process for brain function. The authors found that [prenatal stress] disrupted the [oligodendrocyte lineage], leading to [myelination deficits] and potentially contributing to [neurobehavioural disorders] such as [attention deficit hyperactivity disorder (ADHD)] and [anxiety]. The study emphasizes the importance of understanding the mechanisms underlying these effects and exploring potential interventions to mitigate the consequences of [prenatal stress] on brain development.
Myelination in the Desert: The Impact of Prenatal Stress on Brain Development
This study underscores the significant impact of [prenatal stress] on [myelination], a critical process for brain development and function. The disruption of the [oligodendrocyte lineage] due to [prenatal stress] could lead to [myelination deficits] and potentially increase the risk of [neurobehavioural disorders]. These findings highlight the need for strategies to mitigate the effects of [prenatal stress] and support healthy brain development.
A Desert of Possibilities: Exploring Therapeutic Interventions for Myelination Deficits
The desert of [myelination deficits] can be a challenging landscape for individuals facing [neurobehavioural disorders]. This study emphasizes the importance of exploring potential interventions to address the consequences of [prenatal stress] on [myelination]. Further research into [neurosteroid-based interventions] and other therapeutic approaches may offer hope for restoring healthy brain development and mitigating the impact of [prenatal stress] on behavior.
Dr. Camel's Conclusion
The desert of brain development can be a complex and unpredictable environment. This study shines a light on the hidden dangers of [prenatal stress] and its impact on [myelination]. Just as a camel adapts to the harsh desert conditions, we must continue to explore strategies to support healthy brain development and mitigate the consequences of [prenatal stress]. The quest for effective interventions is a journey through a vast desert of research, requiring dedication and ingenuity to ensure a brighter future for those impacted by [prenatal stress].
Date :
- Date Completed 2022-03-14
- Date Revised 2022-03-14
Further Info :
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