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Protective Effect of Natural Antioxidant Compounds on Methimazole Induced Oxidative Stress in a Feline Kidney Epithelial Cell Line (CRFK).
Author: BadinoPaola, CandelloneAlessia, GirolamiFlavia, JarriyawattanachaikulWatanya, MeineriGiorgia, NebbiaCarlo
Original Abstract of the Article :
The treatment of choice for feline hyperthyroidism is the administration of the antithyroid drug methimazole. Both the endocrinopathy and the drug adverse reactions (e.g., hepatotoxicosis, gastrointestinal disorders, and renal injury) are partly due to oxidative stress and redox unbalance. This stud...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541200/
データ提供：米国国立医学図書館（NLM）
Protecting Feline Kidneys: A Natural Approach to Methimazole-Induced Oxidative Stress
The treatment of [feline hyperthyroidism] presents challenges, with [methimazole] often used as a primary therapeutic agent. This study examines the [oxidative stress] induced by methimazole in [feline kidney epithelial cells] and investigates the protective effects of [natural antioxidants], [quercetin] and [resveratrol]. The study's findings highlight the potential of these antioxidants to mitigate methimazole-related [renal toxicity] and improve treatment outcomes for hyperthyroid cats.
Harnessing the Power of Natural Antioxidants
The study demonstrates the [protective effects] of [quercetin and resveratrol] against [methimazole-induced oxidative stress] in [feline kidney epithelial cells]. This finding suggests that these natural compounds could play a crucial role in [reducing methimazole-related side effects] and enhancing the overall well-being of hyperthyroid cats. The study's results encourage further research into the therapeutic potential of [natural antioxidants] in managing feline hyperthyroidism.
A Holistic Approach to Feline Health
Caring for our feline companions requires a [holistic approach], considering both [pharmacological and non-pharmacological interventions]. The findings of this study highlight the potential benefits of [natural antioxidants] in supporting feline health. It is essential to [consult with a veterinarian] to discuss the best course of action for your cat, taking into account their individual needs and medical history.
Dr.Camel's Conclusion
Just as a camel navigates the desert seeking oases of water, we must seek ways to protect our feline friends from the harmful effects of medications. This study reminds us of the power of nature and the potential of natural antioxidants to enhance feline health. By embracing a holistic approach to pet care, we can provide the best possible support for our animal companions.
Date :
- Date Completed n.d.
- Date Revised 2021-10-26
Further Info :
Related Literature
English
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