Capmatinib successfully overcomes tepotinib-induced intolerable peripheral edema.

Author: InoueTakako, KawamuraTakahisa, KuharaHanako, KumagaiToru, KunimasaKei, NishinoKazumi, TamiyaMotohiro

Paper Details 
Original Abstract of the Article :
In May 2020 and February 2021, capmatinib and tepotinib, respectively were approved by the Food and Drug Administration (FDA) for the treatment of metastatic non-small cell lung carcinoma harboring mesenchymal-epithelial transition (MET) exon 14 skipping alterations. Herein, we present a case of int...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671889/

データ提供:米国国立医学図書館(NLM)

Capmatinib Successfully Overcomes Tepotinib-Induced Peripheral Edema

This case report describes the successful use of capmatinib to overcome intolerable peripheral edema caused by tepotinib, both medications used to treat metastatic non-small cell lung carcinoma. The report highlights the distinct effects of these two MET inhibitors on peripheral edema, showcasing the potential for switching medications to manage this adverse event. The case underscores the need for individualized treatment approaches in managing cancer therapies, tailoring treatment plans to the unique needs of each patient.

Tailored Cancer Treatment Strategies

This case report demonstrates the importance of personalized cancer treatment strategies. The different effects of capmatinib and tepotinib on peripheral edema highlight the need for close monitoring of patients and a flexible approach to treatment. The ability to switch medications to manage adverse events, such as peripheral edema, is a crucial aspect of personalized medicine, allowing for more effective and tolerable treatment outcomes.

Optimizing Cancer Treatment Outcomes

By documenting the successful use of capmatinib to overcome tepotinib-induced peripheral edema, this report provides valuable insights into the management of adverse events in cancer treatment. The ability to switch medications based on individual patient needs is crucial for optimizing treatment outcomes and improving patient quality of life. This case study underscores the importance of ongoing research and clinical vigilance in navigating the complexities of cancer treatment.

Dr. Camel's Conclusion

Just as the desert's landscape can shift and change with the wind, cancer treatment requires a flexible and adaptable approach. This case study underscores the importance of personalized treatment strategies, allowing healthcare providers to navigate the complexities of cancer treatment and adapt to the unique needs of each patient. By embracing a flexible approach and remaining vigilant in monitoring patient response, we can optimize treatment outcomes and improve the quality of life for cancer patients.

Date :
  1. Date Completed 2022-02-08
  2. Date Revised 2022-02-08
Further Info :

Pubmed ID

34695875

DOI: Digital Object Identifier

PMC8671889

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Languages

English

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