Paper Details 
Original Abstract of the Article :
Carbonic anhydrase IX/XII (CA IX/XII), are cell-surface enzymes typically expressed by cancer cells as a form of adaptation to hypoxia and acidosis. It has been widely reported that these proteins play pivotal roles in cancer progression fostering cell migration, aggressiveness and resistance to fir...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8667884/

データ提供:米国国立医学図書館(NLM)

Sulphonamide Carbonic Anhydrase Inhibitors: A New Weapon in the War Against Cancer

The field of oncology is constantly seeking new and effective treatments for cancer. This study investigates the potential of sulphonamide carbonic anhydrase inhibitors (CAIs) as antiproliferative agents against various cancer cell lines. The researchers compared the inhibitory and antiproliferative effects of acetazolamide, SLC-0111, and C18, different sulphonamide CAIs, on glioblastoma, bladder, and pancreatic cancer cell lines. The study's findings suggest that these CAIs exhibited significant antiproliferative activity against these cancer cell lines, highlighting the potential of CAIs as promising therapeutic agents for treating cancer. The research emphasizes the importance of further research into the mechanisms of action and potential clinical applications of these CAIs.

A New Oasis of Hope: Sulphonamide CAIs Show Promise as Antiproliferative Agents

This study offers a beacon of hope in the ongoing fight against cancer, revealing the potential of sulphonamide CAIs as antiproliferative agents. It's like discovering a new oasis in the vast desert of cancer research – a place of promise and potential for new and effective treatments. The study's findings suggest that CAIs may hold significant therapeutic potential, offering hope for patients seeking effective treatments and potentially improving outcomes for those battling cancer.

Navigating the Sands of Cancer Treatment: The Potential of Sulphonamide CAIs

The study's findings underscore the importance of exploring new and innovative therapeutic approaches for cancer. It's like navigating a challenging desert journey – understanding the various pathways to treatment and exploring new options can significantly impact the outcome. The research emphasizes the need for further investigation into the mechanisms of action and potential clinical applications of CAIs, potentially leading to new and effective therapies that target these important enzymes.

Dr.Camel's Conclusion

This study highlights the potential of sulphonamide carbonic anhydrase inhibitors (CAIs) as promising therapeutic agents for treating cancer. It's a reminder that the field of oncology is constantly evolving, seeking new and innovative treatments to improve the lives of patients battling this devastating disease. The study's findings offer a glimmer of hope, suggesting that CAIs may hold significant therapeutic potential and contribute to a brighter future for cancer patients.

Date :
  1. Date Completed 2022-02-23
  2. Date Revised 2022-10-28
Further Info :

Pubmed ID

34894950

DOI: Digital Object Identifier

PMC8667884

Related Literature

SNS
PICO Info
in preparation
Languages

English

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